Hairloss in the family

HARVEST

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Does anyone have older brothers with no hairloss? Mine is 6 years older and has no hairloss and I'm diffuse thinning all over. This makes me think that it may not be simple male pattern baldness but something different. I've been on various antidepressants for a few years due to one reason or another and I think that may be the problem.
 

ryan272

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can i ask you guys, do you know the best website to get finastride 5mg as this is going to work out a lot cheaper than using propicia which i have been on for 7 years
 

antonio666

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it is a genetic lottery,no one in my family has anything less than a norwood 1 aprt from maternal grandfather and he did no start to lose hair until he was 55,
 

Nick4441

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My younger Brother (2yrs younger) lost his hair over 10yrs ago yet I still had a full head of hair up until beginning of last year when I started losing. My cousins lost theirs at 20.

Now i'm fighting like hell to keep mine!...

Antipressents nearly all have hairloss as a side effect. Don't take them..
 
G

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antonio666 said:
it is a genetic lottery,no one in my family has anything less than a norwood 1 aprt from maternal grandfather and he did no start to lose hair until he was 55,

You just said the magic words right there. That seems to be a very common story around here, it seems that the baldness gene usually gets inherited from maternal grandfather. Same here, my mother even has like 10 brothers and only 1 of them is bald (and they're aged 50-75). Apparently their mother (my maternal grandfathers wife) didn't have the balding gene, and only one of them got it from their father.
 

hair today gone tomorrow

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GrowHairGrow! said:
antonio666 said:
it is a genetic lottery,no one in my family has anything less than a norwood 1 aprt from maternal grandfather and he did no start to lose hair until he was 55,

You just said the magic words right there. That seems to be a very common story around here, it seems that the baldness gene usually gets inherited from maternal grandfather. Same here, my mother even has like 10 brothers and only 1 of them is bald (and they're aged 50-75). Apparently their mother (my maternal grandfathers wife) didn't have the balding gene, and only one of them got it from their father.

no...my maternal grandfather had a good hair until he died...in fact everyone on my moms side had nice hair...My dads side EVERYONE has some degree of balding...mostly nw6-7s.....so it can come from either side.
 
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hair today gone tomorrow said:
[quote="GrowHairGrow!":885e3]
antonio666 said:
it is a genetic lottery,no one in my family has anything less than a norwood 1 aprt from maternal grandfather and he did no start to lose hair until he was 55,

You just said the magic words right there. That seems to be a very common story around here, it seems that the baldness gene usually gets inherited from maternal grandfather. Same here, my mother even has like 10 brothers and only 1 of them is bald (and they're aged 50-75). Apparently their mother (my maternal grandfathers wife) didn't have the balding gene, and only one of them got it from their father.

no...my maternal grandfather had a good hair until he died...in fact everyone on my moms side had nice hair...My dads side EVERYONE has some degree of balding...mostly nw6-7s.....so it can come from either side.[/quote:885e3]

Yeah I know it can be inherited from either side, but it seems to be more common to get it from the mothers side.
 

hair today gone tomorrow

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GrowHairGrow! said:
[quote="hair today gone tomorrow":5a75b][quote="GrowHairGrow!":5a75b]
antonio666 said:
it is a genetic lottery,no one in my family has anything less than a norwood 1 aprt from maternal grandfather and he did no start to lose hair until he was 55,

You just said the magic words right there. That seems to be a very common story around here, it seems that the baldness gene usually gets inherited from maternal grandfather. Same here, my mother even has like 10 brothers and only 1 of them is bald (and they're aged 50-75). Apparently their mother (my maternal grandfathers wife) didn't have the balding gene, and only one of them got it from their father.

no...my maternal grandfather had a good hair until he died...in fact everyone on my moms side had nice hair...My dads side EVERYONE has some degree of balding...mostly nw6-7s.....so it can come from either side.[/quote:5a75b]

Yeah I know it can be inherited from either side, but it seems to be more common to get it from the mothers side.[/quote:5a75b]

not really...from what ive read its 51% moms side 49% dads side...coin flip
 

docj077

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Personally, I think that it's all Mom's side if it truly is genetic hair loss with regards to the androgen receptor. The androgen receptor gene is on the x chromosome, so if there is a defect, then it is obviously inherited from the mother. If it's the result of androgen overproduction or other factor, then I don't consider that to be defective androgen receptor mediated hair loss.

There are probably plenty of men out there with a defective androgen receptor that are protected from its effects by having 5AR enzymes that produce less DHT or they may have more aromatase to convert testosterone to estrogen before it gets converted to DHT.

There are probably some men out there that have relatively normal androgen receptors, but 5AR enzymes that overproduce DHT.

That's a guess, but it sure explains how some guys can suddenly have male pattern baldness with no family history or how it can so efficiently skip multiple generations on the mothers side. Plus, it seems like male pattern baldness is associated with multiple mutations with a possible triplet repeat mutation. That mutation will demonstrate anticipation, which will mean that the disease will be worse with each new generation.
 

hair today gone tomorrow

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docj077 said:
Personally, I think that it's all Mom's side if it truly is genetic hair loss with regards to the androgen receptor. The androgen receptor gene is on the x chromosome, so if there is a defect, then it is obviously inherited from the mother. If it's the result of androgen overproduction or other factor, then I don't consider that to be defective androgen receptor mediated hair loss.

There are probably plenty of men out there with a defective androgen receptor that are protected from its effects by having 5AR enzymes that produce less DHT or they may have more aromatase to convert testosterone to estrogen before it gets converted to DHT.

There are probably some men out there that have relatively normal androgen receptors, but 5AR enzymes that overproduce DHT.

That's a guess, but it sure explains how some guys can suddenly have male pattern baldness with no family history or how it can so efficiently skip multiple generations on the mothers side. Plus, it seems like male pattern baldness is associated with multiple mutations with a possible triplet repeat mutation. That mutation will demonstrate anticipation, which will mean that the disease will be worse with each new generation.

I dunno Doctor...i mean like i just said my moms side of the family all had nice hair..both my uncles and my grandfather god rest his sole died with only a mature hair line...in his 80s...all had much better than average hair..

my dads side....everyone suffers from hair loss...my dad is a nw6 all my uncles on his side are at least nw5s and my grandfther on his side was a nw7...not to mention my grandmother on his side started losing her hair when she hit her 60s...

this leads me to believe it can be inherited from either mother or father..

2 of my brothers are also suffering from hair loss...my older brother 25 and my younger brother who is 18 just started thinning out...

what are the chances that all 3 of us have something other than male pattern baldness causing our hair loss?
 
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