sk8charlie
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Don't get confused between Hair Cloning (HC) and Hair Multiplication (HM). HC is using stem cells (found in bone marrow, hair cells, embryonic) and triggering them to re-create hair follicles only. The reason why we can clone a sheep from stem cells is because eventually, that is what the stem cell is programmed to do. It's very complicated to understand without a science background, but basically each and every cell, whether it is a stem cell or not has the book of directions to make a whole new you. The beauty of stem cells is that they are NOT programmed or assigned to use a certain chapter of directions to create a certain body part. Regular cells only use/read a certain chapter of the directions it has; it has the whole book, but only uses and only can use certain chapters. Stem cells can be triggered to use all or some of the chapters. That is why it is easier to clone a whole organism, rather than just a specific body part because it is harder to know the certain signals it takes to trigger a cell to become say, a hair cell. Or in otherwords, it is harder to tell the cell to just read or restrict certain chapters of a book than allow it to read the whole book. On the drawback, the newly cloned individual will have less telomeres, and thus age quicker. As we saw with dolly the sheep, the poor sheep had arthritis and other geriatric ailments even though she was very young. Those are some obstacles that stem cell research has yet to fix.
HM, on the other had, is gathering and culturing cells, and then re-inserting these cells back into the scalp. Cells always divide, until they die usually by degredation, when the products it makes becomes corupt and foreign to the body. (Cancer cells are just that, cells that are corupt, they multiply immensly, do not follow any chemical signals, and they produce byproducts that can be toxic to the body. Normally these cells would be tagged as non-self and destroyed, but they are not dude to genetic factors related to the immune system, etc) The beauty of stem cells is that when they divide, one of them stays a stem cell, and the other matures to become say a hair follicle eventually. Therefore, you will always have a resivorie of stem cells. Only certain organs have stem cells, bone marrow and hair cells being most popular. That is why we age, our non stem cells divide less rapidly as we get older, then we see wrinkles etc etc. The decreased ability of cell regeneration (not speaking of stem cells) is AGING... That's it folks, lack of regeration causes impaired organ functioning.
DHT and other hair loss factors strict the bloodflow, nutrients to the cell and thus all cells die stem cell or not. Once a stem cell is dead, it is dead, it will not be able to regereate itself. This is why people who are bald for long periods of time have extreme difficulty with growing hair back from dormant follicles. Because in actuality, their hair folicles are either extremely miniturized, or absent. The blood is the cells way to get food, without blood or with minimal blood, atrophy of the cell results. This is balding my friends. We know DHT is a culprit, but there may be many many factors....
HM will circumvent this phenomenona by insterting cells taht are resistant to DHT and hair loss factors. These hairs stay on our heads for ever due to genetic factors we are not sure of. All we know is that they will be there, and so the cells we take from them, will produce hair that will stay. HM, will use stem cells from these follicles and create new hair cells that will be injected back into the scalp and hopefully be able to manifest into a hair follicle. It is not cloning. In fact, this is what goes on in your body, HM is basically taking it out of the body, and putting the cells back into the body where appropriate. Oh ya, if you inject a hair cell in your head, it will divide into a stem cell and a hair cell. We dont' know why, it just does, it's because hair cells have that special ability to regenerate itself. And the body only keeps a certain amount of stem cells, it's not like a perpetual cycle.. We have less stem cells than hair cells for sure but if a stem cell dies, then it will be replaced etc.
Honeslty my explanation is quite curtailed, it takes a long time to understand biological processes to even fathom how much we DO NOT KNOW about our bodies especially at the cellular level. Honeslty, and I do not want to sound pessimistic, but the dangers of HM, being uncontrollable cells growing (basically cancer cells), and the risk of it matastisizing (spreading) is quite dire and so I highly doubt that the FDA will let HM or HC slide with ease. Who knows though, maybe hair cells will be good and stay hair cells and follow chemical orders in the body, instead of growing uncondtrollably and spreading to say your brain and causing brain cancer.... hopefully they will but we have to put it in a humans head or heads to know so we gotta start from somewhere... fingers crossed....
HM, on the other had, is gathering and culturing cells, and then re-inserting these cells back into the scalp. Cells always divide, until they die usually by degredation, when the products it makes becomes corupt and foreign to the body. (Cancer cells are just that, cells that are corupt, they multiply immensly, do not follow any chemical signals, and they produce byproducts that can be toxic to the body. Normally these cells would be tagged as non-self and destroyed, but they are not dude to genetic factors related to the immune system, etc) The beauty of stem cells is that when they divide, one of them stays a stem cell, and the other matures to become say a hair follicle eventually. Therefore, you will always have a resivorie of stem cells. Only certain organs have stem cells, bone marrow and hair cells being most popular. That is why we age, our non stem cells divide less rapidly as we get older, then we see wrinkles etc etc. The decreased ability of cell regeneration (not speaking of stem cells) is AGING... That's it folks, lack of regeration causes impaired organ functioning.
DHT and other hair loss factors strict the bloodflow, nutrients to the cell and thus all cells die stem cell or not. Once a stem cell is dead, it is dead, it will not be able to regereate itself. This is why people who are bald for long periods of time have extreme difficulty with growing hair back from dormant follicles. Because in actuality, their hair folicles are either extremely miniturized, or absent. The blood is the cells way to get food, without blood or with minimal blood, atrophy of the cell results. This is balding my friends. We know DHT is a culprit, but there may be many many factors....
HM will circumvent this phenomenona by insterting cells taht are resistant to DHT and hair loss factors. These hairs stay on our heads for ever due to genetic factors we are not sure of. All we know is that they will be there, and so the cells we take from them, will produce hair that will stay. HM, will use stem cells from these follicles and create new hair cells that will be injected back into the scalp and hopefully be able to manifest into a hair follicle. It is not cloning. In fact, this is what goes on in your body, HM is basically taking it out of the body, and putting the cells back into the body where appropriate. Oh ya, if you inject a hair cell in your head, it will divide into a stem cell and a hair cell. We dont' know why, it just does, it's because hair cells have that special ability to regenerate itself. And the body only keeps a certain amount of stem cells, it's not like a perpetual cycle.. We have less stem cells than hair cells for sure but if a stem cell dies, then it will be replaced etc.
Honeslty my explanation is quite curtailed, it takes a long time to understand biological processes to even fathom how much we DO NOT KNOW about our bodies especially at the cellular level. Honeslty, and I do not want to sound pessimistic, but the dangers of HM, being uncontrollable cells growing (basically cancer cells), and the risk of it matastisizing (spreading) is quite dire and so I highly doubt that the FDA will let HM or HC slide with ease. Who knows though, maybe hair cells will be good and stay hair cells and follow chemical orders in the body, instead of growing uncondtrollably and spreading to say your brain and causing brain cancer.... hopefully they will but we have to put it in a humans head or heads to know so we gotta start from somewhere... fingers crossed....
