gyno side effect from topicals

[StoptheMadness]

Since topicals (excluding minoxidil) help inhibit the formation of dht, can this inhibition cause an overall loss of hormonal levels that would lead to gyno symptoms? Or do the topicals only target the composition of dht in the scalp?

 

[Lessofarockstar]

Since topicals (excluding minoxidil) help inhibit the formation of dht, can this inhibition cause an overall loss of hormonal levels that would lead to gyno symptoms? Or do the topicals only target the composition of dht in the scalp?

If there is systemic absorption, then systemic side effects are possible. Normally topical solutions are meant to work only topical though. And therefore there should be no systemic effects. Are you thinking of any particular topicals?
Only thing I have heard of with noticeable systemic absorption is when people do topical dutasteride or finasteride. But that absorption isn't even proven as far as I know.

 

[StoptheMadness]

LoaRS,
I have started to add revivogen, but it seems there is absolutely no consensus that it, and others like it, cause gyno. I am probably being paranoid to some degree, but if one reads enough on the internet about possible side effects, we know that "no possible side effects from the topicals" is not entirely true.

What does "systemic" absporption actually mean? The worst part is for some people who have used anti-androgens the effects of gyno linger long afterwards. But that is probably ony a few people who have this problem. I wanted to use reviovgen to halt my hairline recession, but it is too unkown and I am having 2nd thoughts about this drug.

One thing I did come across is spironolactone (whether taken orally or topically or avodart has a MUCH higher incidence of gyno symptons due to the aggressive stoppage of antiandrogens that are needs to keep muscaluture in males).

http://www.plasticsurgery4u.com/procedure_folder/male_breast/gynecomastia_causes.html

 

[Lessofarockstar]

LoaRS,
I have started to add revivogen, but it seems there is absolutely no consensus that it, and others like it, cause gyno. I am probably being paranoid to some degree, but if one reads enough on the internet about possible side effects, we know that "no possible side effects from the topicals" is not entirely true.


What does "systemic" absporption actually mean? The worst part is for some people who have used anti-androgens the effects of gyno linger long afterwards. But that is probably ony a few people who have this problem. I wanted to use reviovgen to halt my hairline recession, but it is too unkown and I am having 2nd thoughts about this drug.

It's fair to be worried about gyno, but I doubt that revivogen will cause gyno. finasteride, dutasteride and oral spironolactone is definetely some medicines that have caused gyno for some people. But dont worry about revivogen. I really think that the chance of that is very very slim.
Systemic absorption in this context just means that the treatment which is only meant to work at the follicular level/scalp level gets apsorbed through the skin and has systemic effects through the blood stream (thereby lowering DHT throughout your body).

One thing I did come across is spironolactone (whether taken orally or topically or avodart has a MUCH higher incidence of gyno symptons due to the aggressive stoppage of antiandrogens that are needs to keep muscaluture in males).

http://www.plasticsurgery4u.com/procedure_folder/male_breast/gynecomastia_causes.html

DHT blockers and spironolactone is a combination that some transsexuals use, so yes it is known to have feminizing effects. Especially in combination. I am currently using topical spironolactone myself as I had gyno problems with finasteride. I have been looking for evidence of topical spironolactone causing any systemic effect and I am yet to see any. Have you? And are you having any problems at the moment?

 

[StoptheMadness]

This from gynecomastia.org. spironolactone made their list......
http://www.gynecomastia.org/content/treatment/sideffect.shtml

..but I don't know if it means spironolactone taken topically. How do we know that just by using topicalls that they won't cause systemic effects by getting into the blood stream? Is that enought that we think we are applying to our scalp that it won't get in systemically?

I have no problems so far with revivogen although it's been 3 weeks of regular use. Add to the fact it's not FDA approved it just compounds whether I feel this is a safe drug, even though it's endorsed by this site. But this site has really no idea what, if any, revivogen causes sides. There is one poster here who claimed he was getting gyno due to revivogen but that's just one person.

 

[Lessofarockstar]

I think they are referriing to spironolactone taken orally. But that said I cannot tell you that there is absolutely no risk of systemic absorption with topical spironolactone. But it seems unlikely to cause a problem.
For revivogen I would say that the chance of that causing problems is way smaller.
If I were you I would stick with it, and if you do get problems from it, you can quit it. But it is more likely to be caused by finasteride than by revivogen. And the chance of getting gyno from finasteride is fairly small.

You probably know the symptoms of gyno. As long as you dont experience any, stop worrying about it. You'll drive yourself crazy.

 

[StoptheMadness]

rockstar,
I appreciate your response. Good luck with your treatment. I will still continue to take it due to the seemingly small chance of these side effects.