Getting Winlevi Or Compounded Clascoterone (cb-03-01) For Those Outside Of The Us

[constrictedvoid]

Hello,

So as many of you may be aware, Winlevi (1% clascoterone cream, for acne) has been FDA approved recently, and is planned to be available on the market in the US early next year. However, it seems it won't be available outside of that. I have read that some people are trying to make agreements with compounding pharmacies to be able to get them higher concentration versions (as a liquid) to be used more effective for hair loss. Now I'm wondering a number of things. Are there any compounding pharmacies who would send this outside the US? Is that even illegal to do?
Or is the only way to either personally go to the US and try and sneak it back, or have someone who lives in the US send you some? If so, I'd imagine many here are interested in making such agreements.

Please discuss.

 

[constrictedvoid]

Feel free to move this to the antiandrogens subforum if it's more appropriate there by the way, I don't really follow this forum these days.

 

[Redgate]

You can already get pharma-grade CB (and RU) from alibaba. Don't see why you'd want to go through the trouble of sourcing from the US.

 

[jamesbooker1975]

You can already get pharma-grade CB (and RU) from alibaba. Don't see why you'd want to go through the trouble of sourcing from the US.

You mean, Home made lab China ? No, thanks.

 

[constrictedvoid]

Right, well, yeah, I'd prefer to source a more "legitimate" product, and not need to have independent testing done etc.

Is no one else here highly interested in sourcing CB from the US once it releases? I'm surprised there isn't a lot of buzz about that.

 

[constrictedvoid]

We've already been over that. Apparently the pharmacies will not have access to the raw powder so they won't be able to compound it at 7.5%. 1% won't do anything for your hair.

What makes you think they won't have access to it? To my knowledge it's quite common in dermatology to have strong products, or products without particular ingredients compounded.

 

[constrictedvoid]

https://www.hairlosstalk.com/intera...-acne-fda-approval.129237/page-6#post-1911024

It's just a rumor from a derm involved in the trial, but we'll find out soon. Either way you're not going to get anyone to ship it to you from the US.

Well, I already have someone who will ship it to me. And if customs stop it I'd consider flying in to get it.

 

[constrictedvoid]

It's illegal to do that, so you must be paying him quite a premium. Sounds like you have more money than brains so go for it.

What's up with the bad attitude? I suppose that's why I mostly stopped visiting these forums years ago.

 

[blub10]

Still nobody got an idea how to get your hands in 1% from the US?

 

[nick123]

Still nobody got an idea how to get your hands in 1% from the US?

If it's the chemical you're after then science.bio can supply it. I'm not sure 1% will be enough. I'd say at the very least use 2.5% twice a day.

 

[blub10]

I am talking about the final 1% creme, I would give it a shot. Does Science.Bio source it from China?

 

[mooreu]

Creams that are formulated for use on the face may be difficult to use on the scalp. Especially if you have a fair amount of hair.

 

[HairOnFire]

Hello,

So as many of you may be aware, Winlevi (1% clascoterone cream, for acne) has been FDA approved recently, and is planned to be available on the market in the US early next year.

It's a safe bet that the brand-name product is going to be absurdly expensive when it hits the market, IMO. As in, it's going to be out of reach for most bald guys. And for the results you can expect to get, it will be very poor value when considering the amount of money you'll have to spend on it.

You'd likely have to source the active chemical from overseas to make this a practical treatment for hair loss.

 

[blub10]

Creams that are formulated for use on the face may be difficult to use on the scalp. Especially if you have a fair amount of hair.

I am currently just thinning at the Hairline and temples so it would be okay for me

 

[blub10]

It's a safe bet that the brand-name product is going to be absurdly expensive when it hits the market, IMO. As in, it's going to be out of reach for most bald guys. And for the results you can expect to get, it will be very poor value when considering the amount of money you'll have to spend on it.

You'd likely have to source the active chemical from overseas to make this a practical treatment for hair loss.

I cant imagine it will be more expense than Latisse so I would still give it a try

 

[mooreu]

I am currently just thinning at the Hairline and temples so it would be okay for me

There's also the issue of skin penetration. A topical for acne may only need to remain on the dermis to be effective. Any topical for hair maintenance/growth will need to reach the hair follicle. This is all anecdotal as Winlevi has not been trialed for hair loss.

 

[Seuxin]

We don't have to use the Acne cream, at 1%, it will be totally useless. We juste have to find a reliable source to buy CB at a good price. Science.bio is a reliable seller.....The CB probably come From China...like every raw molecules...Comming from China is not an issue if the purity is OK.

 

[hypetraintime]

Here's how you would get it legit.

1. Find the FDA equivalent for your own country
2. Find the process where they outline the process to import unapproved medication. Usually under a heading like 'compassionate use' or 'special access'. Example for Canada
3. Generally speaking, most places have a process where a health care professional can prescribe an unapproved compound. This process changes from country to country. Some countries only allow access if you're dying, but others allow access if the risk to your health is low (in this case). In this case, you would want Clascoterone prescribed at a specific concentration (1% would be easiest to get approval because winlevi, higher %'s may or may not be approved). Nothing to do with a vehicle should be included at this stage, that's the compounding pharmacy's job.
4. HARD PART Find a doctor who will be open going through the relevant process for you. They will be the one driving the process and it can be quite time consuming.
5. Assuming you get the prescription and your country approves your doctor's request, you would take your prescription to a compounding pharmacy and they are responsible for importing, compounding and dispensing. If your country doesn't have a pharmacy which can compound it then idk.
6. It doesn't stop there. Usually after it's prescribed, your doctor is required to monitor you and report and adverse effects etc.. Example for Canada. It's not a big deal though if your doctor is okay with it.

Alibaba = easy to get, but you have no idea what you're getting or whether your DIY solution is even stable / works.
Legit = hard/long to get the first dose, but you know what you're getting and life is easy after.

Generally, if one person in your country has gone through this process for Clascoterone, it basically gets auto approved for prescriptions. The first time is the hardest. Good luck.

 

[el_duterino]

If you look at the clascoterone studies, even the lowest amounts worked to maintain baseline over time. In fact you don't need that much, if you also use other drugs such as minoxidil and stemoxydine in combo.
With hair cut real short most could maintain with 25mg a day provided the scalp is porous - more on this below.

The key is to make the scalp porous, fight male pattern baldness from different angles at the same time, and keep hair short.

If I remember, the cream will be 1% and 10g, and its an acne cream so it would need to be dissolved in 50% of ethanol to be fluid enough to apply over hair, so you have 10,000mg x 1% = 100mg of CB in one tube which lasts 4 days at 25mg/day.

At 50 USD per gram of CB, from labs in China with lower purity, based on the latest results of only 50% purity, we can estimate the equivalent of 100 USD per gram of real CB, so a Chinese Winlevi tube equivalent costs maybe 10 USD.
If we can source these Winlevi tubes for around 10 USD, then its the equivalent of buying the stuff from China today, minus the fluctuating quality issues, and risks of getting the real stuff each time, ordering, customs etc... You would have to test each batch each time and then you don't even know if you get the same batch.

You would need to apply 5ml per day of the Winlevi derived topical instead of the 3ml as per studies, since its diluted in ethanol but you can apply twice a day in separate times or even mix it with minoxidil or stemox.

How to make scalp porous :

this is a key factor and will decide how successful any topical be, like minoxidil etc.. some people do micro needling, I prefer to make my scalp porous by applying lots of ethanolic topicals, and over time the scalp becomes quite porous so I need a lot less of the drug to achieve the same effect.

I found this out using topical RU for over 9 years - without using finasteride or dutasteride

We also have studies showing that even drinking alcohol (ethanol drinks) can make the skin more porous.

 

[NorwoodGuardian]

If you look at the clascoterone studies, even the lowest amounts worked to maintain baseline over time. In fact you don't need that much, if you also use other drugs such as minoxidil and stemoxydine in combo.
With hair cut real short most could maintain with 25mg a day provided the scalp is porous - more on this below.

The key is to make the scalp porous, fight male pattern baldness from different angles at the same time, and keep hair short.

If I remember, the cream will be 1% and 10g, and its an acne cream so it would need to be dissolved in 50% of ethanol to be fluid enough to apply over hair, so you have 10,000mg x 1% = 100mg of CB in one tube which lasts 4 days at 25mg/day.

At 50 USD per gram of CB, from labs in China with lower purity, based on the latest results of only 50% purity, we can estimate the equivalent of 100 USD per gram of real CB, so a Chinese Winlevi tube equivalent costs maybe 10 USD.
If we can source these Winlevi tubes for around 10 USD, then its the equivalent of buying the stuff from China today, minus the fluctuating quality issues, and risks of getting the real stuff each time, ordering, customs etc... You would have to test each batch each time and then you don't even know if you get the same batch.

You would need to apply 5ml per day of the Winlevi derived topical instead of the 3ml as per studies, since its diluted in ethanol but you can apply twice a day in separate times or even mix it with minoxidil or stemox.

How to make scalp porous :

this is a key factor and will decide how successful any topical be, like minoxidil etc.. some people do micro needling, I prefer to make my scalp porous by applying lots of ethanolic topicals, and over time the scalp becomes quite porous so I need a lot less of the drug to achieve the same effect.

I found this out using topical RU for over 9 years - without using finasteride or dutasteride

We also have studies showing that even drinking alcohol (ethanol drinks) can make the skin more porous.

Nice to see CB expert comes back. I recall I have read something about the serious sides of CB in somewhere in this forum, do you think of any possible serious sides?