finasteride/dutasteride Effect On Semen Quality/color

[abovedagame]

This is a personal question but I hope some of u will chime in.

Ive been on finasteride for over a decade. Recently added dutasteride a few times a week to my finasteride. Ever since I've been on finasteride my semen has turned almost clear. My last gf would comment on it. The consistency is not necessarily watery but the color is what worries me. The fact that it's clear kind of scares me. I've read this can be a sign of decreased sperm count due to finasteride/dutasteride. I've been thinking about having sperm count tests done. I'm scared that the Doctor will advise me to stop finasteride/dutasteride.

Any experience with this?

 

[Silber]

Almost all of the volume consists of liquid from the prostate, and not semen. The whiteness is not a sign of semen, but of zinc in the prostatic fluid. I would therefore not be concerned about watery semen, which most users of finasteride and dutasteride experience. I actually see this as a good sign. It tells you that the drugs not only protects you from hair loss, but from enlarged prostate as well.

 

[abovedagame]

Almost all of the volume consists of liquid from the prostate, and not semen. The whiteness is not a sign of semen, but of zinc in the prostatic fluid. I would therefore not be concerned about watery semen, which most users of finasteride and dutasteride experience. I actually see this as a good sign. It tells you that the drugs not only protects you from hair loss, but from enlarged prostate as well.

Thank you for the response. Everything I read pointed towards the fact that semen gets the white/opaque color from the high concentration of sperm. Do u happen to have a source?

There was also a small study that caught my eye which was done by gsk. Showed dutasteride decreased sperm concentration by 23% and it stayed that way for 6 months after stopping. Two people even had sperm counts drop greater than 90%.

Effect on Semen Characteristics
The effects of dutasteride 0.5 mg/day on semen characteristics were evaluated in normal volunteers aged 18 to 52 (n = 27 dutasteride, n = 23 placebo) throughout 52 weeks of treatment and 24 weeks of post-treatment follow-up. At 52 weeks, the mean percent reductions from baseline in total sperm count, semen volume, and sperm motility were 23%, 26%, and 18%, respectively, in the dutasteride group when adjusted for changes from baseline in the placebo group. Sperm concentration and sperm morphology were unaffected. After 24 weeks of follow-up, the mean percent change in total sperm count in the dutasteride group remained 23% lower than baseline. While mean values for all semen parameters at all time-points remained within the normal ranges and did not meet predefined criteria for a clinically significant change (30%), 2 subjects in the dutasteride group had decreases in sperm count of greater than 90% from baseline at 52 weeks, with partial recovery at the 24-week follow-up. The clinical significance of dutasteride’s effect on semen characteristics for an individual patient’s fertility is not known.