finasteride - dutasteride - bye bye sex

[jimjams]

So what are your thoughts on the latest findings of finasteride & dutasteride then?

I have read this a lot recently due to recent trials proving you could lose your erections and libido, in some cases forever.

http://www.theregister.co.uk/2011/03/08 ... impotence/

 

[cristi2011]

So what are your thoughts on the latest findings of finasteride & dutasteride then?

I have read this a lot recently due to recent trials proving you could lose your erections and libido, in some cases forever.

http://www.theregister.co.uk/2011/03/08 ... impotence/

Bulshiiiiiiiiiiiiiit!!!
Come on, some people suffer from impotence. These who took finasteride only found something to blame. it may be other causese, it may be only psuchological, etc. Or simply they're crazy.
What would be the explanation to forever impotence?? If the effects of the drug are definitive, they should also keep their hair forever after stopping finasteride, which i think it's not the case.
And if you ask me, bewteen a complete head of hair and complete libido i choose the hair every day!
And some claim that too much sex(or masturbation) affects your hair, so, anyway you should be moderate.

 

[Tom1985]

LOL

You don't get laid much do you cristi?

 

[Ende]

So what are your thoughts on the latest findings of finasteride & dutasteride then?

I have read this a lot recently due to recent trials proving you could lose your erections and libido, in some cases forever.

http://www.theregister.co.uk/2011/03/08 ... impotence/

Bulshiiiiiiiiiiiiiit!!!
Come on, some people suffer from impotence. These who took finasteride only found something to blame. it may be other causese, it may be only psuchological, etc. Or simply they're crazy.
What would be the explanation to forever impotence?? If the effects of the drug are definitive, they should also keep their hair forever after stopping finasteride, which i think it's not the case.

I don't give a sh*t about you being ignorant, but don't talk like you know the facts. No further hair loss is a common symptom of the "post finasteride syndrome". Your dick doesn't work with a wrecked endocrine system. The symptoms appear to be permanent, but I believe that they're reversible with drugs. Some people haven't been normal for 10 YEARS after using Propecia for some MONTHS.

 

[cristi2011]

Who are these people? And who SCIENTIFICALLY proved that propecia is the cause??
And how many are they? let's say, 10-20 in the world?
Come one, the probability to be affected by that post-invented syndrome is lower than the probability to die tomorrow in a car crash.
And, you see, some say that finasteride even looses its effect with time, so you take it and it doesn't have effect, and you tell me that you simply quit it and remain with the effect FOREVER??
Hope you are not based on opinions on the internet. There are many crazy freaks out there in the world, who have plenty of time to access the internet and post stuff...
What 10 years? Come on, this is a more recent "psychosis".

 

[Ende]

I've first hand experience.

Finasteride can easily induce secondary hypogonadism, because DHT is the estrogen antagonist.

 

[Ende]

Most people don't have evidence, since a blood test isn't mandatory before prescribing Propecia, but I know of one person who has baseline values;

I used Finasteride for 10 month while on it i experience low libido, ED, water retention. 2 weeks after quiting if felt normal again, but then, over 5 days i gradually developed symptoms of hypogonadism. Went to see the Doctor. and got blood work done, it showed i had very low Testosterone compared to what i used to have before taking finasteride, i was diagnosed with secondary hypogonadism, the Doctor. suggest i waited to see if i would get better, i accepted. During the next 15 month after quiting i experienced ups and downs regarding symptoms but never improved to my normal self.
Tired of waiting and with my life negatively affected i visited the Doctor. again and told him i wasn't much better. I did blood tests again and they showed i still had very low Testosterone.

I'm now on a small course of TRT (sustanon 250 every 15 days) to try to recover my T production according to my doc´s prescription. But i know this will not do much, i've read allot about endocrinology and treatments, the best way to recover my production would be with anti estrogens and hcg. but my Doctor. didn't listen so i'm kind of worried that he might not know much about this, and he is supposed to be the best in my country in this filed!

my natural T production was 906ng/dl (245 - 800).
15 month after stopping finasteride my T was 345ng/dl (245 - 800) and my Free T, the one that really matters, was 8.5 pg/ml (8.7 - 54), my E2 was 17 pg/ml (<30) it is a good value but i think a little bit to high for so little Free T, prolactin was mid range.

 

[Ende]

What 10 years? Come on, this is a more recent "psychosis".

Yeah, remember you said that if you develop side effects and chose to ignore them for a while - because Merck tells you that they'll subside if you continue treatment. You'll discover the truth soon enough.

 

[hairhoper]

I don't doubt that finasteride/dutasteride can cause impotence in extreme cases but that is a really lazy article. It doesn't get the basic facts right, for instance it says that Dutasteride is approved for male pattern baldness, which it isn't, it has no references to any recent proof and it has a thoroughly unsympathetic and mocking attitude towards male pattern baldness sufferers.

bothered baldies

Many of these chaps resort to the use of medications containing 5?-RIs, hoping perhaps in many cases to ease their path to passionate interludes in ladies' boudoirs.

Unfortunately in a tragic give-with-one-hand-take-with-the-other style bitchslap-of-fate situation

Whoever wrote this article can literally f*** off and die in a fire.

 

[cristi2011]

You may be right, but why would that be permanent?
And finasteride doesn't have any direct connection with DHT, it only alters alpha-reductase type II. And only by 60%.
DHT may be the estrogen antagonist, but what is the role of normal testosterone then?? An effect of finasteride is even raise in T.
My opinion is those who have permanent side-effect are just unlucky dudes.
I know there are people in the world who had big problems or even died due to trivial medications such as aspirin. every medication is a possible risk, it doesn't mean we must be obsessed by the side effects.
And some people's dick simply doesn't work or stops working even if they don't touch propecia.
PS: Now i read your article. It's nonsense, come on! That guy had less testosterone?? Propecia doesn't affect testosterone at all! It affects alpha reductase, which transforms T in DHT! So on propecia you 'll have more free T!!

 

[Ende]

There are several reasons for ED, and your mind is powerful and could easily give you ED as well, but finasteride alters hormone ratios. Morning erections - which are dependent on an optimal testosterone/estrogen ratio disappear if you develop side effects from finasteride. It's a physical problem.

Finasteride lowers the DHT level around 70%, by blocking all the reductase type 2 enzymes which converts testosterone to DHT. Testosterone is the male hormone, although women have small amounts too. It regulates libido in women. Testosterone is able to convert to both DHT and estrogen.

The testosterone and estrogen level increases by 15% when you begin treatment with finasteride, but in some cases the estrogen level continues to raise (and suppress the testosterone production). This gives you side effects.

I believe that the risk of developing side effects from Propecia is small, but it doesn't mean that finasteride couldn't easily induce secondary hypogonadism. All it takes is a little extra body fat, and your body suddenly has a lot of more aromatase enzymes which converts testosterone to estrogen.

I believe that DHT is the hormone which maintains the testosterone/estrogen ratio, because it's the estrogen antagonist. If you develop side effects from finasteride, you're DHT deficient, and I believe that's why side effects persist after quitting the drug. If the DHT/estrogen ratio changes in favor of estrogen, well... You'll never recover without drug support.