Hello All,
Just wanted to share my method of extracting the S-Equol from Equelle tablets.
Normally you would just crush the tablet and disolve the contents, unfortunately the majority of the Equelle contents tablets are non disolvable in Ethanol and from 600mg tablet only 2.5mg is S-Equol, the rest is just binder.
I normally do 4 tablets at a time so Ethanol quantities mentioned here are based on 4 tablets, which I do weekly.
Instructions:
Wash your tablets, this will remove the talc, magnesium sterate and titanium oxide outer coating form the tablet. It washes off easily and you can see when you are done as the actual contents are a beigish color.
Dry off you wash tablets with a paper towel.
Crush the tablets into a powder and pour the contents into a clear container that you can easily shake.
Add 20ml of Ethanol to the crushed tablets and shake for a couple of minutes.
Let the mixed solution settle, after about 5 minutes you will see that the binder will settle to the bottom with a cloudy solution above it.
Extract the solution with a long pipette, make sure that you do not extract the binder whilst trying to extract the solution. You will see that the liquid in the pipette is a slight pinkish colour, this is the S-Equol.
You then add 20ml back to the container of the remaining binder and repeat the process. The liquid you extract will be less pink the second time round and even less so the third time round.
In total you will have 60ml of liquid containing around 8mg (accounting for 20% not being extracting) of S-Equol.
Just wanted to share my method of extracting the S-Equol from Equelle tablets.
Normally you would just crush the tablet and disolve the contents, unfortunately the majority of the Equelle contents tablets are non disolvable in Ethanol and from 600mg tablet only 2.5mg is S-Equol, the rest is just binder.
I normally do 4 tablets at a time so Ethanol quantities mentioned here are based on 4 tablets, which I do weekly.
Instructions:
Wash your tablets, this will remove the talc, magnesium sterate and titanium oxide outer coating form the tablet. It washes off easily and you can see when you are done as the actual contents are a beigish color.
Dry off you wash tablets with a paper towel.
Crush the tablets into a powder and pour the contents into a clear container that you can easily shake.
Add 20ml of Ethanol to the crushed tablets and shake for a couple of minutes.
Let the mixed solution settle, after about 5 minutes you will see that the binder will settle to the bottom with a cloudy solution above it.
Extract the solution with a long pipette, make sure that you do not extract the binder whilst trying to extract the solution. You will see that the liquid in the pipette is a slight pinkish colour, this is the S-Equol.
You then add 20ml back to the container of the remaining binder and repeat the process. The liquid you extract will be less pink the second time round and even less so the third time round.
In total you will have 60ml of liquid containing around 8mg (accounting for 20% not being extracting) of S-Equol.
