Eren
Established Member
- Reaction score
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Hi guys,
Some of us notice brain fog, anxiety, depression etc. when on finasteride. In my case, I don't know if finasteride really is the only culprit as I already had anxiety and insomnia due to male pattern baldness before I had ever taken even a microgram of finasteride.
I am off of finasteride now for ten days and feel much better though there have been times that I was ON finasteride and felt great too (those days are very rare). My mood has improved drastically at the 9th day after quiting finasteride.
Getting off of finasteride indefinitely would mean being a Norwood 7 in 6 months and getting anxiety and depression due to male pattern baldness (been there, done that). That's not all that great either.
I want to try 0.0625 mg of finasteride by getting 1 mg and cutting it into 16 pieces (I can try) instead of the ususal 5 mg (and cut it into quarters).
If one has mental sides due to finasteride, most likely dihydroprogesterone, also known as allopregnanedione, plays a role. The issue that I have is that serum DHT at 0.05mg of finasteride is suppressed for 50% compared to 70% for 1mg of finasteride. Scalp DHT, however, is suppressed for 60% at 0.05mg and approximately 63% at 1mg.
If scalp DHT is barely affected by the aforementioned dosages, would it be worthwile to try? Has anyone ever tried a dosage that low?
I don't know how much less 5ar2 is inhibited at any dose of finasteride and what consequences that has for the hormones. Inhibiting 10% 5ar2, will that lead to a 10% reduction of DHT, DHP etc? Or isn't there a one-to-one connection between 5ar2 and several associated hormones?
I'll try the lower dosage anyway somewhere in February and will post to let you guys know whether it made a difference for me.
Thanks in advance for any input.
Some of us notice brain fog, anxiety, depression etc. when on finasteride. In my case, I don't know if finasteride really is the only culprit as I already had anxiety and insomnia due to male pattern baldness before I had ever taken even a microgram of finasteride.
I am off of finasteride now for ten days and feel much better though there have been times that I was ON finasteride and felt great too (those days are very rare). My mood has improved drastically at the 9th day after quiting finasteride.
Getting off of finasteride indefinitely would mean being a Norwood 7 in 6 months and getting anxiety and depression due to male pattern baldness (been there, done that). That's not all that great either.
I want to try 0.0625 mg of finasteride by getting 1 mg and cutting it into 16 pieces (I can try) instead of the ususal 5 mg (and cut it into quarters).
If one has mental sides due to finasteride, most likely dihydroprogesterone, also known as allopregnanedione, plays a role. The issue that I have is that serum DHT at 0.05mg of finasteride is suppressed for 50% compared to 70% for 1mg of finasteride. Scalp DHT, however, is suppressed for 60% at 0.05mg and approximately 63% at 1mg.
If scalp DHT is barely affected by the aforementioned dosages, would it be worthwile to try? Has anyone ever tried a dosage that low?
I don't know how much less 5ar2 is inhibited at any dose of finasteride and what consequences that has for the hormones. Inhibiting 10% 5ar2, will that lead to a 10% reduction of DHT, DHP etc? Or isn't there a one-to-one connection between 5ar2 and several associated hormones?
I'll try the lower dosage anyway somewhere in February and will post to let you guys know whether it made a difference for me.
Thanks in advance for any input.
