Epibiotech presented their results on pig skin model

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Joxy

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Epibiotech CEO Sung Jong-hyeok said that through the presentation of the results of the non-clinical test conducted by the company, it was confirmed that the number of hairs increased by 40% and the hair thickness by 30% after 1 month after transplantation of human dermal papilla cells in pig skin. He also explained that the non-clinical toxicity test of EPI-001, a dermal papilla cell pipeline, was completed in June, and that it will apply for an IND in the second half of the year and enter the phase 1 clinical trial in 2023.

www.pharmnews.com

에피바이오텍-연세대 종합약학연구소,탈모 혁신신약 개발 심포지엄 성료

탈모치료제 전문 연구개발 기업 에피바이오텍(대표 성종혁)이 연세대학교 종합약학연구소와 공동 주최한 '탈모 치료를 위한 혁신 약물 개발(Innovative drug discovery for hair-loss therapy)' 심포지엄을 6월 30일 성공적으로 마쳤다. 첫 번째 세션은 학계에서 연구 중인 최신 탈모 기전 연구에 대한 내용으로 경북대학교 성영관 교수가 인간 모낭 세포 모발 유도성에 영향을 미치는 배양 조건 및 유전자에 관한 연구를, 아주대학교 김재호 교수가 입자 미세패턴 기반 세포 배양기판을 활용한 모낭세포 3D 조직체
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RagnarLothbrok

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ty, pretty interesting

what about follicular neogenesis? or its only meant to strength weakened hair?
 
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Zon Ama

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Isnt this actually very good news?
Stemore is taking ages to prove their concept on pigs, while epibiotech just did
 
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Super Metroid

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HMI 115 IS THE CURE dude said:
is it 40% of non vellus hairs? And within what region did they test? It’s so hard to trust these kinds of numbers these days
Click to expand...

Yeah indeed.

What does an "40% increase" even mean? If you have no hair left in a specific region, the 40% increase would amount to nothing.

And there is of course the usual caveat, will progress pass the 6-12 months mark/
 
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HMI 115 IS THE CURE dude

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Super Metroid said:
Yeah indeed.

What does an "40% increase" even mean? If you have no hair left in a specific region, the 40% increase would amount to nothing.

And there is of course the usual caveat, will progress pass the 6-12 months mark/
Click to expand...
there also has to be a reason why they only chose to report post 1 month transplantation numbers. If you go through all the effort to transplant human DP cells in a pig model, you would think they would be pretty incentivized to wait longer than 1 month
 
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JohnDoe5

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HMI 115 IS THE CURE dude said:
there also has to be a reason why they only chose to report post 1 month transplantation numbers. If you go through all the effort to transplant human DP cells in a pig model, you would think they would be pretty incentivized to wait longer than 1 month
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1. What if the area they implanted the cells regrew all the hair that could possibly fit in that area, in which case there would be no point in putting more time into the study because the technique obviously results in full regrowth.

2. Or maybe they were thrilled by the results so they wanted to release early results and the study will continue for more months but given that they plan to start human trials in 2024 it seems like the study is likely completed.
 
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