https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392855/
We summarize the effects of bergamot (extract, juice, essential oil, and polyphenolic fraction) on cardiovascular, bone, inflammatory, skin diseases, mood alteration, anxiety, pain, and stress.
This review included a total of 31 studies (20 studies on humans with 1709 subjects and 11 in animals (rats and mice)).
In humans, bergamot‐derived extract (BE) exerts positive effects on hyperlipidemia with an oral dose from 150 mg to 1000 mg/day of flavonoids administered from 30 to 180 days, demonstrating an effect on body weight and in modulating total cholesterol, triglycerides, LDL, and HDL.
Studies in animals confirm promising data on glucose control (500/1000 mg/day of BE with a treatment lasting 30 days) are available in rats.
In animals models, bergamot essential oil (BEO, 10 mg/kg or 20 mg/kg daily for 20 weeks) increases bone volume, decreases psoriatic plaques, increases skin collagen content, and promotes hair growth.
Bergamot juice (20 mg/kg) is promising in terms of pro‐inflammatory cytokine reduction. In humans, aromatherapy (from 15 to 30 min) does not appear to be useful in order to reduce stress, anxiety, and nausea, compared to placebo. Compared to baseline, BE topical application and BEO aromatherapy reduce blood diastolic and systolic pressure and could have a significant effect on improving mental conditions
The BEO application combined with UVB therapy on psoriatic plaques (30 min before the procedures three times weekly) reduces Psoriasis Area and Severity Index.
In animals, the topical application of bergamot extract for 42 days increased skin collagen content and promoted hair growth significantly.
It seems that a topical application of Bergamot oil/extract in a certain dosage could play an active role in the skin and in promoting hair growth (Shao, 2003; Valkova, 2007). Further studies in humans are needed to confirm this effectiveness and to set a dosage.
We summarize the effects of bergamot (extract, juice, essential oil, and polyphenolic fraction) on cardiovascular, bone, inflammatory, skin diseases, mood alteration, anxiety, pain, and stress.
This review included a total of 31 studies (20 studies on humans with 1709 subjects and 11 in animals (rats and mice)).
In humans, bergamot‐derived extract (BE) exerts positive effects on hyperlipidemia with an oral dose from 150 mg to 1000 mg/day of flavonoids administered from 30 to 180 days, demonstrating an effect on body weight and in modulating total cholesterol, triglycerides, LDL, and HDL.
Studies in animals confirm promising data on glucose control (500/1000 mg/day of BE with a treatment lasting 30 days) are available in rats.
In animals models, bergamot essential oil (BEO, 10 mg/kg or 20 mg/kg daily for 20 weeks) increases bone volume, decreases psoriatic plaques, increases skin collagen content, and promotes hair growth.
Bergamot juice (20 mg/kg) is promising in terms of pro‐inflammatory cytokine reduction. In humans, aromatherapy (from 15 to 30 min) does not appear to be useful in order to reduce stress, anxiety, and nausea, compared to placebo. Compared to baseline, BE topical application and BEO aromatherapy reduce blood diastolic and systolic pressure and could have a significant effect on improving mental conditions
The BEO application combined with UVB therapy on psoriatic plaques (30 min before the procedures three times weekly) reduces Psoriasis Area and Severity Index.
In animals, the topical application of bergamot extract for 42 days increased skin collagen content and promoted hair growth significantly.
It seems that a topical application of Bergamot oil/extract in a certain dosage could play an active role in the skin and in promoting hair growth (Shao, 2003; Valkova, 2007). Further studies in humans are needed to confirm this effectiveness and to set a dosage.