Efficacy Of Adding Peppermint Oil To My Minoxidil

mompo

Established Member
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Would it be relevant to add peppermint oil to my minoxidil or it's useless?
 

HairCook

Experienced Member
My Regimen
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316
Leave it, it might be a pge2 (cox?) inhibitor being overall bad for the hair.
 

HairCook

Experienced Member
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On a mouse that is.
 

Armando Jose

Senior Member
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On a mouse that is.

Ok
https://www.ncbi.nlm.nih.gov/pubmed/?term=minoxidil+peppermint
Peppermint (Mentha piperita) is a plant native to Europe and has been widely used as a carminative and gastric stimulant worldwide. This plant also has been used in cosmetic formulations as a fragrance component and skin conditioning agent. This study investigated the effect of peppermint oil on hair growth in C57BL/6 mice. The animals were randomized into 4 groups based on different topical applications: saline (SA), jojoba oil (JO), 3% minoxidil (MXD), and 3% peppermint oil (PEO). The hair growth effects of the 4-week topical applications were evaluated in terms of hair growth, histological analysis, enzymatic activity of alkaline phosphatase (ALP), and gene expression of insulin-like growth factor-1 (IGF-1), known bio-markers for the enhanced hair growth. Of the 4 experimental groups, PEO group showed the most prominent hair growth effects; a significant increase in dermal thickness, follicle number, and follicle depth. ALP activity and IGF-1 expression also significantly increased in PEO group. Body weight gain and food efficiency were not significantly different between groups. These results suggest that PEO induces a rapid anagen stage and could be used for a practical agent for hair growth without change of body weight gain and food efficiency
 

Armando Jose

Senior Member
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