Effect Of Finastride On Temporal Recession

[Mac12345]

As you can guess from the title I suffer from male pattern baldness at the temples. I recently stopped taking Propecia after sustained shedding and increased thinning of the hairline.

This led me to investigate further. After reading the Propecia study it shows that it didn't examine the results in men with temporal recession. I looked for more information online and this study:
http://www.ncbi.nlm.nih.gov/m/pubmed/22325459/?i=1&from=finasteride temporal alopecia
Which claims to be a study all 4 categories of male pattern baldness actually only enrolled men with vertex male pattern baldness.

So, is there any study that actually documents the effect of Finastride on the temples?

 

[buckthorn]

As you can guess from the title I suffer from male pattern baldness at the temples. I recently stopped taking Propecia after sustained shedding and increased thinning of the hairline.

This led me to investigate further. After reading the Propecia study it shows that it didn't examine the results in men with temporal recession. I looked for more information online and this study:
http://www.ncbi.nlm.nih.gov/m/pubmed/22325459/?i=1&from=finasteride temporal alopecia
Which claims to be a study all 4 categories of male pattern baldness actually only enrolled men with vertex male pattern baldness.

So, is there any study that actually documents the effect of Finastride on the temples?

I'll tell you one thing. finasteride thickened up my hair line after a year. I lost WAY more in the crown and midscalp. So, it just depends on the person.

 

[KO21]

finasteride has done absolutely nothing for my hairline. I've been on it for 9 months and my temples have gotten way worse.

 

[Mac12345]

Same here man, I could only last the 6 months. Had to give it up to remain sane.

 

[Willy_Aer]

It's not a smart move mate. Not enought time to determinate it didn't work for you. And if you were really losing even with finasteride already making its effect, without it for sure you will lose hair even faster.

 

[biddybomb]

I wonder, do people not prone to hairloss suffer from shedding when taking finasteride? I know from my personal experience as an extremely slow receder, I didn't experience one ioata of shedding when I got on 1.25mg a day and I have been on that dose for almost 2 years now. My hair has seen no change whatsoever however I am an extremely slow receder so I wasn't expecting to notice anything tangible anyway.

But yeah, I have heard someone theorize that finasteride increases test and that might be the cause of frontal hairloss.

 

[Mac12345]

I have heard that said before, and maybe your right. But it is just difficult to justify to yourself taking this drug when you can see it making the problem worse, the same problem you took it in the first place.

 

[cyrusthegreat@hotmail.com]

I wonder, do people not prone to hairloss suffer from shedding when taking finasteride? I know from my personal experience as an extremely slow receder, I didn't experience one ioata of shedding when I got on 1.25mg a day and I have been on that dose for almost 2 years now. My hair has seen no change whatsoever however I am an extremely slow receder so I wasn't expecting to notice anything tangible anyway.

But yeah, I have heard someone theorize that finasteride increases test and that might be the cause of frontal hairloss.

i've read this before as well, but i don't think it's due to higher T alone. In a study comparing dutasteride and finasteride, the authors concluded that most of the dht in the scalp resulted from 5ar type 1 activity, and to a lesser degree 5ar type 2 activity, which finasteride inhibits. The authors also noted that when men born without 5ar type 2, but with 5ar type 1 were given T they experienced hairloss. These suggest that for some men hair loss is accelerated when using finasteride (after the shedding phase) because the increased T goes through 5ar type 1 reduction to DHT that further damages hair. Some experienced accelerated loss on finasteride in the vertex, some diffuse, most at the hairline. I think this variation is due to different expression of 5ar type 1 in the scalps of these individuals. Some have more at the hairline, some have more at the vertex, etc. By that logic, dutasteride should help people that continue to lose, or experience increased loss on finasteride. I am one of these people. 18 months on finasteride and nothing but loss. Working up the nerve to move to dutasteride myself. Maybe topical.

 

[jetlife1]

i've read this before as well, but i don't think it's due to higher T alone. In a study comparing dutasteride and finasteride, the authors concluded that most of the dht in the scalp resulted from 5ar type 1 activity, and to a lesser degree 5ar type 2 activity, which finasteride inhibits. The authors also noted that when men born without 5ar type 2, but with 5ar type 1 were given T they experienced hairloss. These suggest that for some men hair loss is accelerated when using finasteride (after the shedding phase) because the increased T goes through 5ar type 1 reduction to DHT that further damages hair. Some experienced accelerated loss on finasteride in the vertex, some diffuse, most at the hairline. I think this variation is due to different expression of 5ar type 1 in the scalps of these individuals. Some have more at the hairline, some have more at the vertex, etc. By that logic, dutasteride should help people that continue to lose, or experience increased loss on finasteride. I am one of these people. 18 months on finasteride and nothing but loss. Working up the nerve to move to dutasteride myself. Maybe topical.

Never have I ever heard the 5AR type 1 is responsible for hair loss. Do you mind sharing that study?

That doesn't make sense to me cause men born without 5AR type 2 don't lose hair and they obviously have normal Testosterone levels.

 

[Willy_Aer]

Could you share pictures showing that your temples got worse after thes 9 months? Sometimes shedding makes you more negative about it even when there is as improvement or maintenance (which could be considered success too).

Never read anything relating type I to baldness. Apparently it makes no sense to me and there are many studies suggesting no correlation

 

[KO21]

I don't have pics but they've receded more and are moving inward to the forelock. Entering nw3 now. Forelock also thinning now. Crown Loss is slowing though.

 

[zzzzz]

If your hair loss is getting worse on finasteride, it means your hair loss would have been even worse then that if you weren't on it. There is no logical reason why finasteride would ever speed up hairloss in the long run

 

[whatevr]

My front kept going at the same speed on Finasteride as it did before I ever took it, meaning it didn't do jack sh*t.

Crown is still decent as it was before.

 

[whatevr]

This. I kept using minoxidil foam and finasteride, only to see my hair thinning and my libido dropping.

Sad thing is, minoxidil gave me really nice results. But what f*****g good is it all, when I can't maintain worth a sh*t? Let's see what RU has to offer now.

 

[Mac12345]

i've read this before as well, but i don't think it's due to higher T alone. In a study comparing dutasteride and finasteride, the authors concluded that most of the dht in the scalp resulted from 5ar type 1 activity, and to a lesser degree 5ar type 2 activity, which finasteride inhibits. The authors also noted that when men born without 5ar type 2, but with 5ar type 1 were given T they experienced hairloss. These suggest that for some men hair loss is accelerated when using finasteride (after the shedding phase) because the increased T goes through 5ar type 1 reduction to DHT that further damages hair. Some experienced accelerated loss on finasteride in the vertex, some diffuse, most at the hairline. I think this variation is due to different expression of 5ar type 1 in the scalps of these individuals. Some have more at the hairline, some have more at the vertex, etc. By that logic, dutasteride should help people that continue to lose, or experience increased loss on finasteride. I am one of these people. 18 months on finasteride and nothing but loss. Working up the nerve to move to dutasteride myself. Maybe topical.

You do have a point. I have read from various sources that dutasteride blocks both types.
If the temporal region is more susceptible to type II this also would explain the increased loss when on finasteride perhaps. finasteride - increased T - increased type II

 

[whatevr]

Before minoxidil I was NW2.5, close to 3 and I was shaving it. f*****g sucked. Hated my life and my image and everything around me.

I keep it longer now but unless I find maintenance I'm headed back there again. f*****g worthless finasteride and sides as well. f*** me.

Hmph... My only choice at this point is to run an aromatase inhibitor or SERM alongside finasteride or dutasteride, and RU (stupid estrogen sides).
Here's my "get hair or die trying" cocktail:
dutasteride + RU + TM30089 + Topical Estrogen + Topical Progesterone + minoxidil + Keto + Arimidex / Tamoxifen

If the gentler stuff fails that's what I will do. f*** it. If I still lose hair on all that, boom headshot.

 

[stachu]

finasteride also did nothing for my hairline. So yeah..

Here's my "get hair or die trying" cocktail:

hahahah add to cyproterone and Shake it baby XD

 

[davesmith420]

I've been on Finasteride for 9 months and my hairline has basically stayed the same if not gotten a little thicker.

 

[KO21]

I've been on Finasteride for 9 months and my hairline has basically stayed the same if not gotten a little thicker.

Lucky guy.

 

[Jeca Tatu]

i've read this before as well, but i don't think it's due to higher T alone. In a study comparing dutasteride and finasteride, the authors concluded that most of the dht in the scalp resulted from 5ar type 1 activity, and to a lesser degree 5ar type 2 activity, which finasteride inhibits. The authors also noted that when men born without 5ar type 2, but with 5ar type 1 were given T they experienced hairloss. These suggest that for some men hair loss is accelerated when using finasteride (after the shedding phase) because the increased T goes through 5ar type 1 reduction to DHT that further damages hair. Some experienced accelerated loss on finasteride in the vertex, some diffuse, most at the hairline. I think this variation is due to different expression of 5ar type 1 in the scalps of these individuals. Some have more at the hairline, some have more at the vertex, etc. By that logic, dutasteride should help people that continue to lose, or experience increased loss on finasteride. I am one of these people. 18 months on finasteride and nothing but loss. Working up the nerve to move to dutasteride myself. Maybe topical.

Oh, f*** me sweet Satan. Being a guy whose problem has been fundamentally temporal recession, I can state by now that the finasteride/dutasteride triggering issue has been one of the greatest dilemmas of my whole adult life. Now I'm reaching a situation similar to @KO21, so I NEED to decided whether to embrace those goddamn drugs or wait a little more while suffering badly. I can't figure out what would be sadder, if it'd be carry the weight of deciding to take the drugs and then wrecking my still-almost-ok hairline or regretting haven't started to take the dick-slayering duo earlier.

In regards to the epigenetic and histologic differences between frotal and vertex regions, do you guys think that this debate is settled? I see little consensus on the mechanism responsible for the afore mentioned different responses. So, for the people on the frontal/temporal-recession-only boat what would be wiser? I'm thinking about starting microdosing them both in topical form. Maybe add some 17-alpha-estradiol too. Or should I stick to topical dutasteride only?...

Clues, anyone?