dutasteride and ketoconazole combo works for me.

[deejack]

the only drug/ drugs that have worked for me are avodart .5 orally in combination with topical keto mixed with topical avodart....iv always understood the logic behind this approach and it does indeed work..iv been on avodart for 4 years(.5 orally) and just maintained maybe slight growth...but when i added the topical avodart and keto i had a bad shed around month 3 and then massive regrowth that i havnt seen in years...im only on month 5 of my new method and getting better every day..i suspect that although dht may be responsible, i believe that other hormones(perhaps testosterone) play a part to a lesser extent)..oral dutasteride cleans up serium dht, topical cleans up scalp dht(both kinds) and the topical keto blocks any other androgens that may play a far smaller part but still inhibit the recovery of already dht damaged follicles.
it appears that this combo has not gone unnoticed
http://cigjournals.metapress.com/conten ... 850484121/
im curious what you guys think..this is one of several studies i found about the combination.

 

[Shift]

This is great!
Congratulations!
Just a short question - how often do you apply topical dutasteride. Did you get irritation from it?
Thanks!

 

[hairhoper]

What are you using for your topical dutasteride? Are you buying liquid dutasteride or making it yourself?

It's interesting you mention such a big improvement when adding a topical antiandrogen. I've started considering adding one lately, but not sure I'd risk buying an experimental (RU or CB) so topical dutasteride (or finasteride) might be an option for me.

Although the study you link to has nothing to do with male pattern baldness it's interesting what they say about Ketoconazole:

Ketoconazole, one of the most commonly used secondary hormonal therapies,
is known to have some activity in CRPC by blocking androgen synthesis via 17-20
lyase, 17-? hydroxylase inhibition

I've heard people refer to Keto as an AA before but always thought it was bollocks? :dunno:

 

[deejack]

i take rubbing alcohol add a couple avodart caps and add some keto cream and apply it with a dropper..yes the study doesnt mention alopecia but the study is relevent none the less because of its inhibition of androgens and the proof that the combination is more effective than any sigle treatment.

 

[fml]

So you dont use minoxidil then for delivery of the topical dutasteride right? Just the rubbing alcohol?

There is another guy (JohnNYC) that uses topical dutasteride and keto but without the internal dutasteride and he swears by it too and says its the first time in years he has had regrowth. I dunno, in a way it sounds like the usual forum desperation like miconozole was but with the dutasteride in there I guess it does have more credibility. I am tempted to actually try this one.

 

[John979]

So you dont use minoxidil then for delivery of the topical dutasteride right? Just the rubbing alcohol?

There is another guy (JohnNYC) that uses topical dutasteride and keto but without the internal dutasteride and he swears by it too and says its the first time in years he has had regrowth. I dunno, in a way it sounds like the usual forum desperation like miconozole was but with the dutasteride in there I guess it does have more credibility. I am tempted to actually try this one.

I posted pics on another forum. unk:

 

[smitysmity]

So you dont use minoxidil then for delivery of the topical dutasteride right? Just the rubbing alcohol?

There is another guy (JohnNYC) that uses topical dutasteride and keto but without the internal dutasteride and he swears by it too and says its the first time in years he has had regrowth. I dunno, in a way it sounds like the usual forum desperation like miconozole was but with the dutasteride in there I guess it does have more credibility. I am tempted to actually try this one.

I posted pics on another forum. unk:

John

Can you send the link? What exactly are you using?

Edit: Nevermind found it. So you're breaking Avodart capsules and mixing them with 5% minoxidil. Sounds good.

1). How are the side effects? Based on what I have read over the months, sounds like the reason we have so many side effects with finasteride and Dura is because we have to consume it. Howabout you?

2). Have you considered mixing both Dutasteride and finasteride together?

3). Have you considered using generic brand Avodart?

 

[fml]

I might be able to answer some of that for John since I have been following that thread myself for quite a while. (Although im on oral finasteride myself because I never trusted the mico side of things). Im not sure if you have found the right thread because this info is in there. The thread John is talking about is a very long thread on the site regrowth dot com. Thread is in General Hair Loss Discussion section and called "Common vaginal yeast infection cream (Monistat)...."

Answers:

1. He does not have sides from his current regimen. He did get sides many years ago when he tried oral finasteride.

2. With regards to mixing finasteride and dutasteride, I doubt he sees the point because over many years he has tried oral finasteride, topical finasteride, minoxidil etc and other stuff and never got results. I assume he wont go back to oral because he fears sides and it didnt work anyway. And topical finasteride on top of topical dutasteride seems redundant. And again, that also did not work previously anyway.

3. Regarding generic dutasteride, he is using brand avodart for piece of mind and does not want to use generic. finasteride is out of patent so legit generic American sources exist. dutasteride is still in patent so generic would have to come from India for a few more years.

 

[John979]

fml;

Thank you, you answered my questions. Regarding sides, there may be some reduced ejaculate but nothing else.

 

[John979]

Let me also add in the last month, I did see a major shed.

However, I did expect that I would not only experience such but that the first few would be dramatic, given that the new growth would be in sync.

My concern is that at about the same time, I tapered off 15% minoxidil and switched to Bimatoprost.

 

[smitysmity]

My concern is that at about the same time, I tapered off 15% minoxidil and switched to Bimatoprost.

I have been shedding pretty badly lately as well but I don't know if it's the RU, Bimatoprost, Prox-N, or new Minoxidil. I will just wait this out and assume that the shedding is good right now and that it means the treatment is going to work just need to give it time.

However, why not do both Minoxidil and Bimatoprost?

I add Bimatoprost to 10%/15% minoxidil. It appears to have dissolved because Bimatoprost takes a while to dissolve because it is chunky but it did dissolve. I had less than 1mg of Bimatoprost per application which is usually 3 little chunks of the substance which I apply to 3ML.

 

[fml]

fml;

Thank you, you answered my questions. Regarding sides, there may be some reduced ejaculate but nothing else.

I assume you experienced that on oral finasteride of course. How long into your dutasteride regimen did it start, can you remember?

Let me also add in the last month, I did see a major shed.

However, I did expect that I would not only experience such but that the first few would be dramatic, given that the new growth would be in sync.

Havent you been on your regimen for about eight or more months now? How long should one continue to expect sheds for? I understand that a lot of your hair is in sync cycle wise, but I thought the growth stage was a couple of years or more. Am I wrong on that? Is regrown hair shedding for rest phase or whatever it is?

John, just to confirm, previously you did not have results from minoxidil alone right? (Just confirming in my head that the addition of dutasteride or keto must be significant.)

My concern is that at about the same time, I tapered off 15% minoxidil and switched to Bimatoprost.

I havent been following new threads much so Im not sure what bimatoprost is. I assume growth stim. How come you switched? Is it meant to be better than minoxidil? Is it a different method? Such that you would not keep the original minoxidil gains?

Edit: Going to read about bimatoprost now. And this CB-01 thing that I keep seeing people talk about.

 

[deejack]

yea i dont see it as a "usual forum desporation move" i mean, i see ordering ru from china, or using miconazole with no studies to back it up or following immortals advice as being desperation move, but i use nothing thats not backed by very good studies. i use only avodart and keto.. from what i have read they are the best and most effective medications to date( that are available from a reliable source) so thers nothing desperate about that.. i used oral avodart and still do but i use the topical every other day and alternate with oral and the keto cream every day..thats it..i tried minoxidil a few years ago but when i read the study, it showed that the first year the density increases but after the first year it begins to decrease to baseline...so you have to continue using it just to have the same amount of hair you would have had , had you never used it.lol..thats crap and i wont do that...if you take minoxidil too long and you stop you will be balder than if you never started!!..better off preventing hairloss with antiandrogens rather than get your hair strung out on "hair crack" besides, the studies show that bimatoprost doesnt do that and after you grow hair with that, you can very well maintain with couple days a week applications...that sounds a little beter so im considering that.