michael barry
Senior Member
- Reaction score
- 14
Dr. Rolf Paus recently has said, in response to a query about cloning, that effective inhibitors of negative growth factorts and pro-growth factors that ensure the release of progrowth factors could be used to make sure hair stays in anagen and doesn't miniaturize and that cloning was basically a bad idea.
I dont agree with this, and believe the creating of new hairs from donor hair cells represents the real short term cure for male baldness, but Paus has a point.
As we learn what dermal papilla-released growth factors inhibit follicle growth, if we find ways to suppress them, we will probably be able to keep follicles growing and not eliciting an immune response over time.
Negative growth factors known in HUMAN (not rat) dermal papilla cells at this point are PKC,
TGF beta 1
TGF beta 2
IL_1
DPPK
FGF-5
Thrombospondin.
External inflammatory cytokines that probably harm the follicle include TNF-alpha
There are probably a few dermal papilla negative growth factors than this, and we dont know of how to suppress all of the ones we know of, but its being worked on.
Im rooting for cloning however, and I think you should too.
I dont agree with this, and believe the creating of new hairs from donor hair cells represents the real short term cure for male baldness, but Paus has a point.
As we learn what dermal papilla-released growth factors inhibit follicle growth, if we find ways to suppress them, we will probably be able to keep follicles growing and not eliciting an immune response over time.
Negative growth factors known in HUMAN (not rat) dermal papilla cells at this point are PKC,
TGF beta 1
TGF beta 2
IL_1
DPPK
FGF-5
Thrombospondin.
External inflammatory cytokines that probably harm the follicle include TNF-alpha
There are probably a few dermal papilla negative growth factors than this, and we dont know of how to suppress all of the ones we know of, but its being worked on.
Im rooting for cloning however, and I think you should too.
