Here's an old alt.baldspot post of mine in which I answered someone else who had also challenged me about the scientific evidence showing that SODs work for hair growth. Here's the complete post:
On Tue, 09 Jul 2002 02:00:16 GMT, honkguy <honk...@hotmail.com> wrote:
>> >BTW, show me one shred of clinical evidence that SODs grow hair on male pattern baldness
>> >sufferers. Don't pull out the "clinical trials" from ProCyte, either, because
>> >I believe those results about as much as I believe Springhair Tonic works.
>>
>> Why do you feel that way, Mitch? I've previously cited three studies
>> on SODs that were published in a medical journal;
>
>For male pattern baldness? Could you posts the references if you get a chance?
Oops... I goofed. They weren't published in a medical journal, they were published in the book "Dermatologic Research Techniques", CRC Press, 1996. They are three consecutive chapters in the book:
Chapter 16: "Phototrichogram Analysis of Hair Follicle Stimulation: A Pilot Clinical Study with a Peptide-Copper Complex" Ronald E. Trachy, Leonard M. Patt, Gordon M. Duncan, and Bernard Kalis. This was done on *human* subjects with male pattern baldness. Both total and anagen hair density increased significantly (anagen hair: +39%) with the larger topical dose of copper-peptide (glycyl-histidine-lysine-valine-phenyalanine-valine), especially when compared to total and anagen hair density LOSSES in the placebo-treated group.
Chapter 17: "Quantitative Assessment of Peptide-Copper Complex-Induced Hair Follicle Stimulation Using the Fuzzy Rat" Ronald E. Trachy, Hideo Uno, Shelley Packard, and Leonard M. Patt. This was done on rats. Copper peptides significantly stimulated hair growth, compared to vehicle.
Chapter 18: "Evaluation of Telogen Hair Follicle Stimulation Using an In Vivo Model: Results with peptide-Copper Complexes" Ronald E. Trachy, Erika D. Timpe, Irene Dunwiddie, and Leonard M. Patt. This was on mice. Copper peptides significantly stimulated hair growth in mice, compared to vehicle; it also exceeded the growth induced by 2% topical minoxidil, which was also tested.
>> and then there's Dr. Proctor's huge clinical experience with them; and
>> then there's my very own experience with Prox-N (emphasis on SODs,
>> obviously) that I've seen with my own two eyes. Why do YOU have such
>> a problem believing that they work?
>As a SOD user, I actually don't have any problem with believing they work; I'm just
>pointing out these agents, which we all seem to place at least some degree in faith
>in, IMHO fall into HairLossTalk.com's definition of "unproven treatments" (as would Revivogen).
>They don't have the large-scale clinical studies like finasteride and minoxidil to
>support their efficacy- essentially, we're relying on smaller, indirect studies and
>Dr. P's expertise with hair loss agents. FDA-approved treatments, as you well
>know, are scarce in this area, so I really believe we've got to work with a much
>looser definition of "unproven."
Ok. What bothered me was your rather vitriolic response ("Don't pull out the "clinical trials" from ProCyte, either, because I believe those results about as much as I believe Springhair Tonic works"), which suggested to me that you thought that copper peptides for male pattern baldness are absolutely positively nothing but a huge scam and ripoff, rather than just something which is relatively lacking in clinical evidence, at least compared to other things like minoxidil, which has been tested for almost two decades. As long as you don't lump copper peptides in with Springhair Tonic, then I don't have a problem with what you said!
Bryan