Do The Cytokines—interleukin-1 Beta, Interleukin-6, And Tumor Necrosis Factor(tnf) Alpha Affect Hair

[ScentlessApprentice]

I'm not up to date on chronic inflammation and hairloss but I came across this study today showing decreased levels of these when using a specially formulated cream containing a certain ratio of cholesterol, free fatty acids, and ceramides. A quick search looks like creams are available with this ratio. Would decreasing levels of these have a benefit to hair?

https://www.ucsf.edu/news/2019/03/413576/skin-repair-eliminates-inflamm-aging-linked-chronic-disease

I also came across this hypothetical model mentioning IL-1 and TNA along with other possible factors involved with AA.

https://www.sciencedirect.com/science/article/pii/S0306987717310411

Anyone more knowledgeable than me have some insight?

 

[ALightInTheDark]

Yes they do.
They are byproduct of DHT/TNF-b etc etc.

 

[BetaBoy]

I don’t know about IL-6 but I know IL-17 is said to be possibly implicated in affecting hair in some negative way. When recieving anti-interleukin IL-17 therapy it has been shown to reverse grey hairs and increase hair counts in atleast one patient with ΑGΑ.