Do hairloss doctors prescribe Oral spironolactone?

mjk258

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At some point I'm interested in adding low-dose spironolactone to add to my Finasteride 1 mg daily.

The reason I would do this would be ensure the effectiveness of the finasteride over the long term.

Would this work?
 

abcdefg

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How does oral spironolactone help ensure success with the propecia? Why would a doctor prescribe you oral spironolactone when your already on propecia and if he does you might want to think about different doctor.
 

mjk258

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abcdefg said:
How does oral spironolactone help ensure success with the propecia? Why would a doctor prescribe you oral spironolactone when your already on propecia and if he does you might want to think about different doctor.

I understand that Oral spironolactone can be dangerous. But under supervision of a doctor and doing blood tests etc., can the risk be well managed?

Finasteride inhibits something like 38% of scalp DHT, would a small dose of oral spironolactone not, indirectly, cause a further DHT inhibition?
 

Bryan

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mjk258 said:
Finasteride inhibits something like 38% of scalp DHT, would a small dose of oral spironolactone not, indirectly, cause a further DHT inhibition?

I tend to doubt that a doctor would prescribe oral spironolactone just to treat hairloss (because of possible lawsuits), but I guess you won't know for sure until you try.
 

antman

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you would probably learn at lot more about oral spironolactone on transgender forums like Susan's Place
 

brian liles

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why would a doctor prescirbe something for hairloss, that has never been proven for hairloss. yes spironolactone has anti androgen affects, but it has never been proven.


Right now ther only thing proven is finasteride. not even dutasteride. dutasteride only works better in some due to the more inhibition of type 2 reductase. type 1 has not impact on hair loss. there are so mnay stidues to prove it.

stay away from spironolactone. transgenders use it.
 

mjk258

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brian liles said:
why would a doctor prescirbe something for hairloss, that has never been proven for hairloss. yes spironolactone has anti androgen affects, but it has never been proven.


Right now ther only thing proven is finasteride. not even dutasteride. dutasteride only works better in some due to the more inhibition of type 2 reductase. type 1 has not impact on hair loss. there are so mnay stidues to prove it.

stay away from spironolactone. transgenders use it.

The only studies I've seen conclude that Dutasteride is far more effective than Finasteride.


Would low dose spironolactone + finasteride under suoervision of a physician be like a middle ground between finasteride and dutasteride?
 

brian liles

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the only reason why duta is more affective than propecia is becuase it inhibits more of the alpha type 2. plus alot of doctors still say there isn't even evidence to even show duta is more effective. it might be just the same, or just slightly better. if duta was in fact better, than glaxo would of pursued an fda approval by now, so they can make millions. not because of its alpha type 1 inhibition abilities. type 1 does not cause hairloss. the psudeohermaphordites had type 1 alpha 5 reductase with normal testosterone levels as well, and never expereinced hairloss due to the, not having the type 2 enzyme.


again in terms of spironolactone. spironolactone only inhibits testosterone, not alpha 5 reducatse type 2. even on spironolactone there will be little testosterone that will bind with the type 2 reducatse enzyme that will produce DHT, and more hairloss. thats why finasteride is way better than spironolactone because it tackles the root source wich is the type 2 enzyme.

plus guys should not be taking spironolactone due to the massive side affects. its given to transgenders lol
 

Bryan

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mjk258 said:
The only studies I've seen conclude that Dutasteride is far more effective than Finasteride.

It's an exaggeration to say that dutasteride is "far more effective" than finasteride. At the standard, recommended doses, it's only a little more effective.
 

Bryan

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brian liles said:
again in terms of spironolactone. spironolactone only inhibits testosterone, not alpha 5 reducatse type 2.

We all know that spironolactone is a proven antiandrogen, but I've seen conflicting claims on whether or not spironolactone is also a 5a-reductase inhibitor. I have an older study which claims that it is a 5a-reductase inhibitor, and another study that claims that it isn't. I honestly don't know which one is correct, and which one is wrong! It may turn out that spironolactone only inhibits 5a-reductase to a small degree.
 
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