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I see that some users on this forum have had success to varying degrees with custom-made topical solutions. Some topical formulas that look promising include fiansteride, minoxidil, spironolactone, daro, and estrogen. I am already using homebrewed 0.4% finasteride/5% min solution, and want to fortify it with at least one more ingredient. I'm leaning towards using an estrogen as the third ingredient, perhaps estradiol, because I 'think' its mechanism of action would be complementary, rather than overlapping, with the other two ingredients. I could be wrong. I would like to hear from those who have tried various DIY topicals. Any advice would be appreciated.