As I'm lurking the internet and looking at different information about Hair Loss I came across an interesting article and different look regarding DHT and hair loss.
There is a common believe that DHT is the primary cause of hair loss by binding to hair androgen receptors and causing follicles to shrink and miniaturize however it requires accumulation of trapped DHT in scalp.
Numerous studies show that bald scalp has increased fat content and skin is fibrotic with reduced blood circulation in the area and DHT accumulates in areas of the skin with reduced blood circulation.
Increases in body fat is consistent with raise of estrogen levels for example women have 30% more body fat than man as a normal levels.
DHT is antagonist of Estrogen in male body so if ratio of Testosterone - Estrogen is low (normal 20-50) the body try to compensate by producing more DHT. Estrogen levels are 7-64 Testosterone levels 270-1100.
Testosterone levels in male body decline by 1.2% each year after puberty so it is compensated by increased percent of testosterone converted to DHT.
Testosterone binding to hair follicle causes hair growth example is around genitals where there is enough blood circulation and free testosterone.
With age there is one more important chemical compound that play in body chemistry SHBG (sexual hormone binding globulin) it increases each year and by age of 40 its presence is larger than testosterone. SHGB binds to free testosterone and this way prevents it from binding to androgen receptors causing body hair to fall off as testosterone s replaced with DHT.
Boosting testosterone levels is not a solution as some percent is converted to estrogen and DHT by 5a reeducaze.
What happens in bone muscles DHT that is carried with blood there is quickly dissolved by 3a reductaze so only testosterone is able to bind to androgen receptors.
DHT is not the enemy when fighting hair loss it is the end result after accumulation of fat in the scalp and reduction of blood flow.
The question is how to prevent accumulation of fat in the scalp and increase blood flow? By increasing ratio of Testosterone vs Estrogen in the body, reducing body fat, increase the blood flow in affected area (scalp massage, dermaroller). In addition appropriate amount of vitamins and nutrients like biotin and proteins need to be present.
There is also one supplement that increases testosterone while lowering Estrogen in male body it is a trace element called Boron (Borax) that is not studied extensively on humans but few studies show 29% increase in free testosterone after 1 month and 47% decrease in Estradiol (its effect on athletes is not significant as their T levels are already high). It was used in bread production as a preservative until 70s and currently as a supplement against osteoporosis and attrite. The effect of Boron on rats is testosterone increase and deprivation leads to hair loss. It helps with calcium and magnesium absorption.
There is a common believe that DHT is the primary cause of hair loss by binding to hair androgen receptors and causing follicles to shrink and miniaturize however it requires accumulation of trapped DHT in scalp.
Numerous studies show that bald scalp has increased fat content and skin is fibrotic with reduced blood circulation in the area and DHT accumulates in areas of the skin with reduced blood circulation.
Increases in body fat is consistent with raise of estrogen levels for example women have 30% more body fat than man as a normal levels.
DHT is antagonist of Estrogen in male body so if ratio of Testosterone - Estrogen is low (normal 20-50) the body try to compensate by producing more DHT. Estrogen levels are 7-64 Testosterone levels 270-1100.
Testosterone levels in male body decline by 1.2% each year after puberty so it is compensated by increased percent of testosterone converted to DHT.
Testosterone binding to hair follicle causes hair growth example is around genitals where there is enough blood circulation and free testosterone.
With age there is one more important chemical compound that play in body chemistry SHBG (sexual hormone binding globulin) it increases each year and by age of 40 its presence is larger than testosterone. SHGB binds to free testosterone and this way prevents it from binding to androgen receptors causing body hair to fall off as testosterone s replaced with DHT.
Boosting testosterone levels is not a solution as some percent is converted to estrogen and DHT by 5a reeducaze.
What happens in bone muscles DHT that is carried with blood there is quickly dissolved by 3a reductaze so only testosterone is able to bind to androgen receptors.
DHT is not the enemy when fighting hair loss it is the end result after accumulation of fat in the scalp and reduction of blood flow.
The question is how to prevent accumulation of fat in the scalp and increase blood flow? By increasing ratio of Testosterone vs Estrogen in the body, reducing body fat, increase the blood flow in affected area (scalp massage, dermaroller). In addition appropriate amount of vitamins and nutrients like biotin and proteins need to be present.
There is also one supplement that increases testosterone while lowering Estrogen in male body it is a trace element called Boron (Borax) that is not studied extensively on humans but few studies show 29% increase in free testosterone after 1 month and 47% decrease in Estradiol (its effect on athletes is not significant as their T levels are already high). It was used in bread production as a preservative until 70s and currently as a supplement against osteoporosis and attrite. The effect of Boron on rats is testosterone increase and deprivation leads to hair loss. It helps with calcium and magnesium absorption.
