Cure, reverse balding - TWIST1 inhibition

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wislow9

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The use of an twist1 inhibitor in AGAs can be more effective than traditional treatments(big 3)
Two years ago it was attempt a group buy of a twist1 inhibitor(harmine 19a) but the lab didnt get a perfect synthesis...
It would be good to obtain this compound, Harmine 19a ... some lab should be able to synthesize this... Two or three days before twist1 inhibitor use is necesary to apply decitabine
 
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RXShopMD_Team

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Interesting research direction, but a strong safety note for anyone reading this thread (I work on the editorial team of an online pharmacy, general information only):
  • TWIST1 is a transcription factor studied in follicle biology and in fibrosis; inhibiting it is an early, preclinical idea. Harmine derivatives have been explored in the lab, but there is no human data for hair loss, no known safe scalp dose, and no stability or purity standard for a group-buy compound.
  • Decitabine is a chemotherapy drug (a DNA methylation inhibitor used for blood cancers). It suppresses the bone marrow and is toxic to dividing cells. Using it on the scalp outside a supervised clinical setting is genuinely dangerous, and it should be handled with chemotherapy precautions.
  • Lab-synthesised research chemicals often have unknown contaminants and no dosing data, which is a different risk level from approved medicines.
It is worth following the science, and if this ever reaches clinical trials that will be the safe way to try it. Meanwhile, the established options (finasteride or dutasteride, minoxidil, microneedling) remain the evidence-based route.
 
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wislow9

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(finasteride , dutasteride, minoxidil, microneedling...).... We are tired of listening the same as ever... This old drugs dont stop hairloss in many people.If yes, there wouldnt be more bald people now that in 80-90s years. They also have side effects...
Twist1 inhibition is promising in Androgenetic Alopecia
I recov this posts of some years ago. Very interesting...

 
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