Crispr Androgenetic Alopecia Patent - New Company Sangamo

[kingjohn]

a new company patented a method of curing Androgenetic Alopecia using crispr at the end of 2017

https://patents.google.com/patent/WO2017197141A2/en?q=Androgenetic&num=100&oq=Androgenetic&sort=new

things are looking up bois

 

[cretin]

f*****g cocksuckers! go public so i can buy shares!

 

[Trichosan]

a new company patented a method of curing Androgenetic Alopecia using crispr at the end of 2017

https://patents.google.com/patent/WO2017197141A2/en?q=Androgenetic&num=100&oq=Androgenetic&sort=new

things are looking up bois

That was quite an epistle! Also, a broad-based patent whose applicable components could take decades to research before any clinical implementation. It's like the beginning of construction of the Large Hadron Collider in the search for the Higgs-Boson. So don't get your follicle in a tickle just yet.

 

[BetaBoy]

CRISPR/Cas9 is far to new of a technology to even consider commercialisation, gene therapies will have an up hill battle proving their safety. This is likely just a company that will sit on this patent until a larger company with actual means and capital to effectively pursue a gene therapy Androgenetic Alopecia treatment is forced to buy it.

 

[Janks16]

Yep. Hurry up and wait.

 

[Xander94]

in the next 50 years

 

[Armando Jose]

2. The genetically modified cell of claim 1, wherein the Androgenetic Alopecia-related gene is prostaglandin D2 synthase (PTGDS), a GPR44 receptor (PTGDR) gene and/or an androgen receptor (AR) gene.

In other embodiments, cells are described that comprise an engineered transcription factor (TF) such that the expression of a gene related to Androgenetic Alopecia is modulated. In preferred embodiments, the gene to be targeted is the androgen receptor (AR), the ectodysplasin A2 receptor (EDA2R), histone deactylases HDAC4 and/or histone deacetylase HDAC9, prostaglandin D2 synthase (PTGDS), GPR44 receptor (PTGDR2, or DP2), the TWIST 1 and TWIST2 transcription factors, WntlOA, WNT3, ITPR2, TARDBP, SUC R1, MBNL1, EBF 1, AUTS2, IMP5, and SSETBP1. Further preferred genes include Hic5/ARA55, TGFpl and 2, DKK1, and SRD5A2

The laboratory have a lot of patent
https://patents.google.com/?assignee=Sangamo+Therapeutics,+Inc.&num=100&sort=new


Wooooo .......

BTW The Ceo probably suffer from male pattern baldness
http://wxpress.wuxiapptec.com/wp-content/uploads/2017/08/WuXi_perspectives_SandyMacrae_WPXRESS.png

 

[Trichosan]

in the next 50 years

Definitely full blown genetic mods by then. I'll have Norwood-1, add five inches to my height and six to the schlong. Not bad for a 117 year old.

But really, the potential for Androgenetic Alopecia tx seems to be ramping up and it could bring more academic interest and competition for commercialization. Positive like never before.

 

[Xander94]

Definitely full blown genetic mods by then. I'll have Norwood-1, add five inches to my height and six to the schlong. Not bad for a 117 year old.

But really, the potential for Androgenetic Alopecia tx seems to be ramping up and it could bring more academic interest and competition for commercialization. Positive like never before.

COuld would in 10 years etc. WE NEED HAIR NOW OR ITS OVER FOR US

 

[Ollie]

Spoke to a buddy who is a Doctor about Crispr...just laughed and said we're literally looking at at least 20 years. The problems in theory are horrendous enough let alone reality.

 

[Hate da Bt]

Spoke to a buddy who is a Doctor about Crispr...just laughed and said we're literally looking at at least 20 years. The problems in theory are horrendous enough let alone reality.

A friend of a friend...
A buddy who is a doctor...
At least ten years...
In the meanwhile, the technology being developed by Sangamo has nothing to do with CRISPR/Cas9...
Bravo, bravo!!!

 

[Ollie]

A friend of a friend...
A buddy who is a doctor...
At least ten years...
In the meanwhile, the technology being developed by Sangamo has nothing to do with CRISPR/Cas9...
Bravo, bravo!!!

Any Gene therapy is decades away. We've got f*****g topical lotions that have been 'in the making' for years and years and we haven't seen a single one yet, and you're putting your optimism in therapies that alter your genetic makeup .

And yes, i'll prefer to take the word of an individual who has been through med school + 4 years doing his PhD and half way through his 7 year Neurosurgical course than a bunch of people trying to form optimism from reading technology reports and patent filings.

 

[Hate da Bt]

Any Gene therapy is decades away. We've got f*****g topical lotions that have been 'in the making' for years and years and we haven't seen a single one yet, and you're putting your optimism in therapies that alter your genetic makeup .

And yes, i'll prefer to take the word of an individual who has been through med school + 4 years doing his PhD and half way through his 7 year Neurosurgical course than a bunch of people trying to form optimism from reading technology reports and patent filings.

Optimism?
Not really.
Your comment is just ...irrelevant.
CRISPR/Cas9 has nothing to do with Sangamo Therapeutics. Period.
Plus, gene editing ain't decades away.

 

[Ollie]

Optimism?
Not really.
Your comment is just ...irrelevant.
CRISPR/Cas9 has nothing to do with Sangamo Therapeutics. Period.
Plus, gene editing ain't decades away.

Lol if you think you'll be walking into an office and someones gonna be altering your genetic make up before 2035.

 

[Trichosan]

Optimism?...

Plus, gene editing ain't decades away.

Correct. https://vector.childrenshospital.org/2017/10/ald-gene-therapy-clinical-trial/

 

[Hate da Bt]

Lol if you think you'll be walking into an office and someones gonna be altering your genetic make up before 2035.

That is not what I meant.
I simply said that gene editing ain't decades away.
It's not that difficult to comprehend, is it?

 

[BalderBaldyBald]

Oopsie !

https://ki.se/en/news/genome-editing-tool-could-increase-cancer-risk

That risk was already identified a long time ago, but they've seen it live now

Who was the true genius that did this DYO gene editing kit again ? This tech is so promising though, w8 and see

 

[NotInmywatch]

we don't even know how GPR44 and AR activation kills hair. what a troll.