Confused about the genetic part :)

[A_Munk3y]

ok, so male pattern baldness is passed down through genetics. I got that much, but what confuses me is what is it that passed down genetically that causes male pattern baldness?

Because if it is passed down genetically, and not something to do with health or something, then why are there talks about working out, and masturbation (although they are not scientifically proven) that can affect male pattern baldness? If it's genetic, then these should have no affect at all, correct?

Or is it that the hair that you have received is more prone to certain things, like DHT and those things are the effects of working out ect (raising testosterone)... If that is the case, then i can understand...

But then, i sometimes read that taking hot showers is bad, and that you should use cold water, and that dying hair is bad ect... If it's genetic, then why should these matter? Since all these have no affect on DHT, and that these are just temporary (like if dying hair damages it, then after it is damaged, and dies off, then the new growth shouldn't grow damaged, should it? Or for example heat makes hair dry, but why should that matter if DHT is the cause of male pattern baldness??) So why should anything that causes temporary hair problems, be a problem for someone with male pattern baldness?

Sorry if i sound like a complete newb, but im just a little confused.

 

[barcafan]

Genetics as in androgen receptor sensitivity. People state working out or masturbating increases androgen levels, so your sensitive receptors get fucked even harder by the higher androgen levels that these activities cause.

 

[A_Munk3y]

ahhh.. i see

but then why is it bad to dye/ bleach hair, or ironing/ hot showers if that has no affect on androgen levels, and would only cause temporary damage, which would grow back normal? (or would it ? ^.^)

 

[mykal_P]

Disregard the whole temperature thing, it was a theory of misterE's and has no scientific backing.If your heads spinning at this point don't worry, their are new theories and products brought up here constantly that we all hear about. It's safe to say you should stick with the big three for proven results.Anything else just make a educated guess based on any results from users here or any studies found.

 

[Lux]

Genetics as in androgen receptor sensitivity.

but as we all learned, every cell of our body contains the same genes.
Why there are no people with bald spots on the back of the head? )

 

[barcafan]

Genetics as in androgen receptor sensitivity.

but as we all learned, every cell of our body contains the same genes.
Why there are no people with bald spots on the back of the head? )

Because they're not as sensitive to androgens?

 

[jonsie150]

genetics isn't fate. it just gives you a predilection for something.life is about a intertwining of environment and genes. just cause you have cancer in your family doesn't mean you'll get it for sure. but you can lower you chances by taking measures such as not smoking.

on the flip side, some people can smoke all their lives and never develop cancer, simply because they don't have the genetic makeup.

 

[s.a.f]

genetics isn't fate. it just gives you a predilection for something.life is about a intertwining of environment and genes. just cause you have cancer in your family doesn't mean you'll get it for sure. but you can lower you chances by taking measures such as not smoking.

on the flip side, some people can smoke all their lives and never develop cancer, simply because they don't have the genetic makeup.

There is nothing stronger than genetics (by a long way) any benifits from outside influences are very small (if at all) especially in the case of m.p.b which is natural condition with no connections to health vs something like cancer.

 

[vauxall]

viewtopic.php?f=11&t=55101

 

[Jokerman]

There is nothing stronger than genetics (by a long way) any benifits from outside influences are very small (if at all) especially in the case of m.p.b which is natural condition with no connections to health vs something like cancer.

Yep, male pattern baldness is an inherited trait.

 

[barcafan]

genetics isn't fate. it just gives you a predilection for something.life is about a intertwining of environment and genes. just cause you have cancer in your family doesn't mean you'll get it for sure. but you can lower you chances by taking measures such as not smoking.

on the flip side, some people can smoke all their lives and never develop cancer, simply because they don't have the genetic makeup.

Think of genetics as how your body responds to stimuli from the outside world.

 

[Lux]

Genetics as in androgen receptor sensitivity.

but as we all learned, every cell of our body contains the same genes.
Why there are no people with bald spots on the back of the head? )

Because they're not as sensitive to androgens?

Sensitivity is defined by genes? So how the hair follicles on the forehead can be more sensitive to DHT if these follicles contains exactly the same genes?
Probably the sensitivity is the same, but some of the mechanical impact can be involved.

 

[Bryan]

Sensitivity is defined by genes? So how the hair follicles on the forehead can be more sensitive to DHT if these follicles contains exactly the same genes?

That's a good question. Here's another closely related one: why do androgens stimulate the growth of most body hair, but suppress the growth of scalp hair? Some day we'll know the answer to those questions.

 

[spiveslude]

Sensitivity is defined by genes? So how the hair follicles on the forehead can be more sensitive to DHT if these follicles contains exactly the same genes?

That's a good question. Here's another closely related one: why do androgens stimulate the growth of most body hair, but suppress the growth of scalp hair? Some day we'll know the answer to those questions.

This question doesnt take into account the complexity of genetics. This type of logic would allow one to ask: If all of our cells have the same genes then why is your index finger located on your hand and not your forehead? I think that recently it was discovered that hairloss is affected by at least 7 different genes. This may account for the variations in hairloss and not a simple yes or no to hairloss.

 

[Bryan]

This question doesnt take into account the complexity of genetics.

Excuse me, but it EMPHASIZES the complexity of genetics! The question points out an apparent difference in the fundamental design of various hair follicles around the body.

 

[karl_h]

The genetic part of hair loss might be referring to the number of DHT receptors that an individual has on their scalp. The more DHT receptors that an individual has on their scalp, the more hair they are going to lose.

Everyone has a different number of DHT receptors on their scalp, and this is one of the reasons for the varying degrees of hair loss that people experience.

 

[Bryan]

The genetic part of hair loss might be referring to the number of DHT receptors that an individual has on their scalp. The more DHT receptors that an individual has on their scalp, the more hair they are going to lose.

Everyone has a different number of DHT receptors on their scalp, and this is one of the reasons for the varying degrees of hair loss that people experience.

I think people pay far too much attention to factors having to do with the overall strength of the androgenic stimulus (like the numbers of androgen receptors, the amount of testosterone that's produced, the amount of the 5a-reductase enzyme that converts it to DHT, etc.), and overlook the manner in which hair follicles respond to the androgenic stimulus (which gets far more to the root of the problem). For example, scalp hair follicles and body hair follicles react in a completely OPPOSITE way to androgens (androgens are actually good for body hair), but that clearly has nothing to do with androgen receptors and those other things. We will have the final answer to balding when we can develop treatments that can change that overall response of hair follicles to androgens. Until then, we're just treading water and biding our time with antiandrogens, 5a-reductase inhibitors, and androgen receptor suppressors.

 

[armandein]

scalp hair follicles and body hair follicles react in a completely OPPOSITE way to androgens (androgens are actually good for body hair), but that clearly has nothing to do with androgen receptors and those other things. We will have the final answer to balding when we can develop treatments that can change that overall response of hair follicles to androgens. Until then, we're just treading water and biding our time with antiandrogens, 5a-reductase inhibitors, and androgen receptor suppressors.

Hi Bryan;

Is there another type of hair respect to androgens?
What happen with hairs around scalp?

Armando

 

[mpbsux20]

The hairs present around the scalp are resistant to DHT so most people are resistant to it.The only cure for baldness would be to clone plenty of such hair follicles and transplant them whenever you show signs of balding.It would take decades for such a technique to be even developed and a few more decades for it to be legalised.

 

[Lux]

The hairs present around the scalp are resistant to DHT so most people are resistant to it.The only cure for baldness would be to clone plenty of such hair follicles and transplant them whenever you show signs of balding.It would take decades for such a technique to be even developed and a few more decades for it to be legalised.

explain to a stupid person. What will be the difference between the cloned one follicle from the back of ur head and the died one on ur forehead? Aren't they of the same genes?
Russian science has already developed the way to scan the cell waves and to place that waves into another one cell so it changes the genes of the cell. So if it's all about genes, it should be suffice to scan the cell waves of ur back and place them onto ur forehead? But seems to me, that there is no difference between cell waves on the back and on the front of ur head.
No offense to anybody, but it's kinda stupid to supress the DHT to maintain ur hair instead of suppressing the sensitivity of the cells to do the same thing. But those few drugs to suppress the sensitivity are not working at all. ((