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- This review article assessed the available evidence on the efficacy of oral supplement ingredients and formulations as they pertain to hair growth. The authors identified no clinical evidence supporting the use of vitamin A, vitamin D, biotin, niacin, selenium, ashwagandha, curcumin, and capsaicin for treatment of hair loss. There is weak evidence for vitamin C and iron supplementation for patients with known iron deficiency. Mild evidence exists for the use of vitamin E and zinc in hair loss conditions in addition to mild evidence for horsetail and methylsulfonylmethane as complementary management for skin and hair health. Some evidence exists for the use of pumpkin seed oil and saw palmetto as additional options for androgenetic alopecia. Finally, marine complexes have exhibited positive effects on hair health.