Can One Manipulate A Drug/solution's Charge By Encasing It In A Charged Vehicle?

Gone

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Oh boy, another question that would-probably-be better-suited-for-a-chemistry-professor-but-I'm-settling-for-this-forum-out of-impatience-and-desperation-for knowledge.

Let's say you had a neutrally charged drug you wanted to use for iontophoresis. You wouldn't be able to use it unless you altered the solution to be ionically positive or negative (iontophoresis requires a charged solution).

Instead of altering the drug's formula, would it instead be possible to encase it in a charged vehicle?
 

what

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bump, anyone know chemistry?

Yes, you need to know the isoelectric point of your compound, then put it into a solution with a pH above or below the pI. This will cause the drug to carry a charge. Positive if you manipulate pH below pI, negative if above pI.
 

Gone

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What does PL stand for? And if you repel the drug with iontophoresis, the entire/drug solution will be moved as one? (As opposed to the vehicle leaving the drug behind). Thank you for the help.
 

Dorasz

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What does PL stand for? And if you repel the drug with iontophoresis, the entire/drug solution will be moved as one? (As opposed to the vehicle leaving the drug behind). Thank you for the help.

pi stands for isoelectric point
 
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