- Reaction score
- 520
I was thinking about the galea theory lately because it explains many things such as why the Norwood pattern is precisely that way. A mechanism I find plausible is:
Compression or tension of the galea -> Restriction of blood vessels to the hair follicles -> Inflammation sets in -> due to inflammation DHT is sent to the scalp -> TGF-β expression increases -> calcification of blood vessels -> hair miniaturization
The first big question is why this tension of the galea happens in the first place. I've read some hypotheses, amongst other things genetic factors. Another hypothesis was about bad body posture stretching the muscles around the neck which in turn create tension of the galea ( https://tmdocclusion.com/2018/07/14/more-on-hair-loss/ ).
Compression or tension of the galea -> Restriction of blood vessels to the hair follicles -> Inflammation sets in -> due to inflammation DHT is sent to the scalp -> TGF-β expression increases -> calcification of blood vessels -> hair miniaturization
The first big question is why this tension of the galea happens in the first place. I've read some hypotheses, amongst other things genetic factors. Another hypothesis was about bad body posture stretching the muscles around the neck which in turn create tension of the galea ( https://tmdocclusion.com/2018/07/14/more-on-hair-loss/ ).