Bored doing some research on male contraception and look what I found!

Captain Hook

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Male oral/injectable contraception has always been an interesting topic of research for me as it seems like something we could see marketed in the near future.

While I was browsing around I came across a website with instructions on how to go about mirroring a male contraception regimen that has been proven in clinical studies, I had to do a double take when I saw our boy Fred in the comments section! First comment too with the unmistakeable polar bear avatar. FredTheBelgian seems to have quite the presence online.

I felt bad though, many of the people attacking him with replies probably had no idea his gynaecomastia was due to finasteride use based on their comments. Gynaecomastia is far less common of a side effect from finasteride than exogenous testosterone, so they blamed him for not being on an aromatase inhibitor, something that isn't normally concomitantly used with finasteride due to lack of necessity.

That being said, from a pharmaceutical science point of view it's nice to see the articles author mentioning to include the aromatase inhibitor anastrozole (Arimidex) along with the testosterone enanthate injections to prevent gynaecomastia due to increased plasma estrogen levels, which is a common side effect for exogenous testosterone use based on its prevalence in clinical studies.

Site in question:

http://www.returnofkings.com/42046/how-to-use-and-obtain-testosterone-for-male-birth-control

References to effectiveness of various hormonal contraception methods in men:

http://press.endocrine.org/doi/full/10.1210/jcem.87.2.8218

http://www.medscape.com/viewarticle/722423_5

http://www.ncbi.nlm.nih.gov/pubmed/8774299

http://www.contraceptionjournal.org/article/0010-7824(77)90025-7/abstract?cc=y=
 
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