Hello guys,
I have the project to made a home-made lotion for hair containing severals stuffs, including Azelaic Acid. The goal is to copy a good lotion like Revivogen and try to add other stuff good for hair, and for cheap.
Why Azelaic Acid ? Because Azelaic Acid is an anti 5AR and a good inti-inflammatory.
I use a standard lotion for hair (containing ethanol) as vehicle for this lotion.
I dumped 5% of Azelaic Acid. When dissolved, i tried the solution : It smell acid, and it burn a little the scalp, it's normal : it's due to the acid.
24hours after....the lotion didn't smell acid..and the lotion didn't burn...
Why ?
I do some search on google and it found severals patent on google claiming Azelaic Acid is unstable in ethanol ! But....there is a few minoxidil with Azelaic acid based on ethanol right ? So why there were no problems ??
For informations, here is the patent :
http://www.google.com/patents/EP0831768A1?cl=en
SO...i'm trying to find another vehicle to coumpound my lotion, i want a liquid form, not a cream.
Any good chemist here ?
I'm thinking to try :
PG 20% / DMSO 5 % / Polysorbate 80 20% / Distilled water.
--> Will this solution be penetrant ??
Any replacement for ethanol ? Maybe another alcool ? Isopropyl alcool ? Oley Alcool ?
Any chemist here ?
I have the project to made a home-made lotion for hair containing severals stuffs, including Azelaic Acid. The goal is to copy a good lotion like Revivogen and try to add other stuff good for hair, and for cheap.
Why Azelaic Acid ? Because Azelaic Acid is an anti 5AR and a good inti-inflammatory.
I use a standard lotion for hair (containing ethanol) as vehicle for this lotion.
I dumped 5% of Azelaic Acid. When dissolved, i tried the solution : It smell acid, and it burn a little the scalp, it's normal : it's due to the acid.
24hours after....the lotion didn't smell acid..and the lotion didn't burn...
Why ?
I do some search on google and it found severals patent on google claiming Azelaic Acid is unstable in ethanol ! But....there is a few minoxidil with Azelaic acid based on ethanol right ? So why there were no problems ??
For informations, here is the patent :
http://www.google.com/patents/EP0831768A1?cl=en
SO...i'm trying to find another vehicle to coumpound my lotion, i want a liquid form, not a cream.
Any good chemist here ?
I'm thinking to try :
PG 20% / DMSO 5 % / Polysorbate 80 20% / Distilled water.
--> Will this solution be penetrant ??
Any replacement for ethanol ? Maybe another alcool ? Isopropyl alcool ? Oley Alcool ?
Any chemist here ?
We need topical Cetrizine but it too expansive. :wacko: