Azelaic acid along with zinc sulphate and vitamin B6

[Phillip]

OK, well i was searching around about azelic acid today. I did read that it can have a dht reducing effect but usually the studies where it did so were along with zinc sulphate and vitamin B6. They were selling a cream on the inhousepharmacy site.

A british study in 1988 suposedly affirmed this.

It says it blocked 90 percent of 5ar activity?

So guys, lets see the oppinions flow in.

I have really been curious for awile about tryin the xandrax 5percent with azelaic acid. Maybe if you could add b6 and zinc somehow than it would be more credible as a dht inhibitor

 

[Guest]

how are you planning to add b6 and zinc to it?

bryan has said that he doubts dr lee's claims about xandrox, and i trust him more than i trust someone trying to sell a product.

 

[beaner]

The only study I've seen with azelaic acid, b6, and zinc was done on foreskins in a test tube but never proved to inhibit DHT in living tissue....I thought that was an Italian study but I could be wrong...please post a link on this study if you have it, my curiosity is sparked

 

[Phillip]

http://www.ayurvedacollege.com/MalePatternBaldness.htm
http://www.inhousepharmacy-europe.com/hair-loss/androgenetic-alopecia.html

There are two links with the same info. I wasnt saying that i was actually going to attempt to add the zinc and b6. I was simply saying if there was a way to do so it would be awesome.

After researching some more, Minoxidil.com is saying that when these products are combined it would make the minoxidil not work so i guess its out with that idea.

http://minoxidil.com/Zinc and B6.htm

I still don't understand why so many people here don't believe that azelaic acid works to inhibit dht? Almost every site that i google seems to say the same thing tht it does infact inhibit. They are also sites that are not selling any products

 

[Bryan]

I still don't understand why so many people here don't believe that azelaic acid works to inhibit dht?

Probably because of the following two facts which I've discussed several times:

1) The complete lack of any POSITIVE in vivo evidence. I don't know of a single experiment ever done with living animals (either humans or laboratory animals) where topical azelaic acid was proved directly to reduce DHT, or even had any effects that could be reasonably interpreted as possibly being a sign of reduced DHT.

2) The existence of some NEGATIVE in vivo evidence, which could be interpreted as evidence against the idea that DHT was being reduced. Those are studies in both humans and laboratory animals in which topical azelaic acid had no effect on the production of sebum (citations available, on request). The reduction of sebum would be an expected result, if DHT were really being reduced.

Such a consistent picture (the lack of POSITIVE evidence, and the existence of some NEGATIVE evidence) is quite damning for azelaic acid, in my opinion.

Bryan

 

[CCS]

i got some B6. It is worthless for hair loss. i'll sell it to anyone who will give me $5 plus shipping. I wasted $20 on it since I did not do my research before buying it.

maybe an overweight guy will buy it from me to up his metabolism. I don't know if it has that effect, but maybe.

 

[hair_tomorrow]

i got some B6. It is worthless for hair loss. i'll sell it to anyone who will give me $5 plus shipping. I wasted $20 on it since I did not do my research before buying it.

maybe an overweight guy will buy it from me to up his metabolism. I don't know if it has that effect, but maybe.

I'm now 8 months + on zix / super zix and 4 months on azaelic acid, and in my case, I believe it's helping.

This is such an inexpensive and cosmetically acceptable set of topical(s) which has has helped some people - so I have no problem always recommending this combo first - before trying any of the more expensive topicals and medications.

 

[Guest]

[ so I have no problem always recommending this combo first - before trying any of the more expensive topicals and medications.

except it's unproven and you may be screwing people by telling them to delay getting on proven topicals and oral meds until they try your unproven formulas. they may lose more hair because of you.

 

[hair_tomorrow]

[ so I have no problem always recommending this combo first - before trying any of the more expensive topicals and medications.

except it's unproven and you may be screwing people by telling them to delay getting on proven topicals and oral meds until they try your unproven formulas. they may lose more hair because of you.

OK - so you'd recommend to a 17 - 18 year old (or anyone for that matter) to go straight to minoxidil and proscar?

I spent two years on the more accepted products (spironolactone, revivogen, xandrox) . . . and I didn't grow a single hair - and in fact lost more in the process. I'm certainly not blaming anyone here who's had any success with any of those products. More power to them.

But at least I know I tried.

In my instance - I wish I would have STARTED w/ zix and azaelic acid.

It's all a crap shoot anyway. What works for you may not work for me and vice-versa.

If people aren't successful w/ zix and or azaelic acid, OK, it's 6 - 9 months down the drain. But at least they wouldn't have spent a fortune to experiment w/ revoivogen, and not be able to go out of the house after applying, and not have to ruin their pillow cases.

I hope no-one ever loses more hair because of me.

 

[Guest]

[quote="hair_tomorrow":48454][ so I have no problem always recommending this combo first - before trying any of the more expensive topicals and medications.

except it's unproven and you may be screwing people by telling them to delay getting on proven topicals and oral meds until they try your unproven formulas. they may lose more hair because of you.

OK - so you'd recommend to a 17 - 18 year old (or anyone for that matter) to go straight to minoxidil and proscar?

I spent two years on the more accepted products (spironolactone, revivogen, xandrox) . . . and I didn't grow a single hair - and in fact lost more in the process. I'm certainly not blaming anyone here who's had any success with any of those products. More power to them.

But at least I know I tried.

In my instance - I wish I would have STARTED w/ zix and azaelic acid.

It's all a crap shoot anyway. What works for you may not work for me and vice-versa.

If people aren't successful w/ zix and or azaelic acid, OK, it's 6 - 9 months down the drain. But at least they wouldn't have spent a fortune to experiment w/ revoivogen, and not be able to go out of the house after applying, and not have to ruin their pillow cases.

I hope no-one ever loses more hair because of me.[/quote:48454]

18 yes on proscar and rogaine, 17 def yes on rogaine no problem, as for proscar at that age i think they should consult with a doctor if under 18.

you may have lost hair with all those products but the facts remain that for most people liek 99%, going with proven remedies like finasteride, dutasteride, minoxidil, copper peptides and nizoral is better for their long term hair goals than going with your ideas.

i wasn't trying to make you feel bad so i hope you didn't take my words the wrong way . i simply advocate going by the first P of the three advocated on this site: use PROVEN products. That thread lists the most proven products to the least proven- not surprisingly finasteride and minoxidil are at the top of the list, because they are the only two fda approved products for hair loss. i'd put dutasteride up there with finasteride obviously.

it's not a crap shoot. yes no results are guaranteed but for the vast majority of people they are better off to start using proven remedies to halt hair loss and possibly regrow rather than wasting valuable time trying stuff like Pr*cerin, Avacor, and your azelaic acid whatever.

 

[hair_tomorrow]

JM - your points are well taken - but going back to my original statement -all the fda approved stuff aside - it's still true that zix alone has helped many (anecdotally anyway - according to forum reports), and that the zix / aa combo has certainly helped me.

The fact that it is so inexpensive compared to just about anything else out there, that you can apply it and your hair looks great afterwards, and that it may help - makes it worth trying, in my opinion.

 

[Guest]

maybe as a supplement to a real proven regimen. i just don't like advising people to take it without a proven dht inhibitor or anti androgen. azelaic acid and zinc have never been proven to work in vivo.

and time is precious. it's much easier to maintain than regrow as we all know. the 6 months they spend on your admittedly inexpensive idea may prove to be very costly in the long run.

 

[CCS]

never mind. I only spent $6 on it. it still has the price tag on it. I'd consider using it, but the GLA should do the trick and not have any filler.

I think it is perfectly ok for hair_tomorrow to recommend it as long as he tells them that other stuff is known to work on a larger percentage of people, and that he is using it because the other stuff did not work for him.

That long post Jayman copy pasted said that DHT is not anabolic to muscle. I don't know if that is true, but I do know that people without 5ar2 develop later. Just trying to guess if 16 year olds can take finasteride.

 

[Nick1990]

ok who still has their hair ?