Any Options For Dupa Sufferers? Any Worth Considering Viviscal?

[z.ali93]

Hi all,

I'm 27 and my hair thinned rapidly from the age of 23/24. I've not been able to style properly and can see my hairline.

I've been taking generic finasteride. for the last 2-3 years. Honestly, I don't know the difference- i can't tell if it's slowed my loss or made no difference, but i still continue to take it.

I've been considering to get FUE transplant for some time now, but will I even get decent results? I just want my hairline and temples filled in.

I've just started derma-rolling and going to begin nofap to see if any improvement.

Also - has anyone had any results using viviscal??

 

[baba_yaga]

Dupa = hair transplant not an option.
You’ve been taking finasteride for 2-3 years. Do you feel you have maintained? Or your hair got worse? (The answer is crucial to get decent advice)
Trying nofap while on finasteride is nothing but a joke. finasteride already nuked 70% of your DHT. Nofap will never ever come close to compensating a tiny fraction of that not-so-sweet DHT.

 

[z.ali93]

Dupa = hair transplant not an option.
You’ve been taking finasteride for 2-3 years. Do you feel you have maintained? Or your hair got worse? (The answer is crucial to get decent advice)
Trying nofap while on finasteride is nothing but a joke. finasteride already nuked 70% of your DHT. Nofap will never ever come close to compensating a tiny fraction of that not-so-sweet DHT.

That's a shame to hear. I see alot of decent results on hair transplant Instagram pages with DUPA, so i wonder what went right for them ?

And it's hard to say with fines. I'm still experiencing episodes of hair loss and my hair is still miniaturising, but i'm not sure if the finesteride stalled it and if it would be worse than not taking it ?

 

[z.ali93]

Here is a post from last year to compare;

https://www.hairlosstalk.com/intera...ranoid-or-do-i-have-dupa.121477/#post-1782768



And here is a picture of what my hair was like from 2015! The hair loss kicked in 2016 and I jumped on fines in 2017.

 

[baba_yaga]

That's a shame to hear. I see alot of decent results on hair transplant Instagram pages with DUPA, so i wonder what went right for them ?

And it's hard to say with fines. I'm still experiencing episodes of hair loss and my hair is still miniaturising, but i'm not sure if the finesteride stalled it and if it would be worse than not taking it ?

You can do a hair transplant, but you're going to loose that hair as your donor is also miniaturizing.

If finasteride is maintaining your hair or it is very slowly progressing, you should stick to it. The fact that you're not sure if you're maintaining is a good sign that finasteride is doing its job. Also shedding is not hair loss. Its normal to shed on finasteride.

Can you post a recent photo of your hair in the same angle as your 2015 photo?

 

[whatintheworld]

I'm not sure you have dupa. Anyone who cuts their hair really short will be able to see scalp.

 

[z.ali93]

You can do a hair transplant, but you're going to loose that hair as your donor is also miniaturizing.

If finasteride is maintaining your hair or it is very slowly progressing, you should stick to it. The fact that you're not sure if you're maintaining is a good sign that finasteride is doing its job. Also shedding is not hair loss. Its normal to shed on finasteride.

Can you post a recent photo of your hair in the same angle as your 2015 photo?

Yeh i feel like I've come too far to stop finesteride now. I think the only time i will probably come off it is when I try for a kid and 2 months off prior to it.

This pic was literally 2 mins ago

 

[baba_yaga]

I think your hair has not changed. Maybe a bit, but thats just from looking at pics. I say stay on finasteride. If you experience CERTAIN worsening, get on duta. There is nothing you can do other than taking anti-androgens. Derma rolling and minoxidil are also a big plus.

 

[dupapls]

i have dupa as well and your hair looks almost identical to mine, with the sides of the scalp being affected the worst. i took finasteride for a year a while ago and it didn't seem to do much for me. i'm not convinced that our hair loss is caused by dht. do you have any scalp issues like itching/inflammation/dandruff/etc?

 

[z.ali93]

i have dupa as well and your hair looks almost identical to mine, with the sides of the scalp being affected the worst. i took finasteride for a year a while ago and it didn't seem to do much for me. i'm not convinced that our hair loss is caused by dht. do you have any scalp issues like itching/inflammation/dandruff/etc?

Not anymore but when my hair loss properly began like 4 years ago, i remember an incredible itchy sensation over my scalp and was shedding a lot. The hair that fell out would have large white bulbs on the tips too.

I can't remember the last time i experienced that

 

[baba_yaga]

i have dupa as well and your hair looks almost identical to mine, with the sides of the scalp being affected the worst. i took finasteride for a year a while ago and it didn't seem to do much for me. i'm not convinced that our hair loss is caused by dht. do you have any scalp issues like itching/inflammation/dandruff/etc?

Dupa is caused by androgens. +95% cases of hair loss are androgenic alopecia.

 

[camille leprevost]

Hello my friend, i am french so i apologise in advance for my english.

I do have the same pattern as you, 28 years old , thinning and overall shedding back, side, and top and my hairline is quite not touched actually. I think it is DUPA and it is similar to female pattern hair loss actually.

Some studies showed that high prolactin level can cause hair on side and back to become sensitive to androgen as well. So might be something to dig in. Also annecdotally, it seems that DUPA sufferer are sensitive to DHT but also to Free testosterone in scalp. Apparently DHT seem to cause localised thinning where testosterone cause diffuse thinning.

If you have been to a dermatologist, i hope she gave you a full bloodwork to do because besides that they are useless,

You need to check for :
-nutritionnal defficiency
-metabolism glucidic ((Glucose, insuline sensitivity,)
- full hormonal check : cortisol, LH ,FSH ,Prolactine, E2,17OH progesterone, progesterone, SHBG, testosterone total, free T, androstanediol G6470, delta 4 androstenedione, DHEA-S, DHT ....
- inflamatory syndrom ...

I am going to do a full blood check this friday, so i will send you the result here in 2 weeks if you want. If you have done a full blood work too, it will be great to compare it to check for similitude.

To tell you a bit about myself i started to lose hair all over since 3 years now.
I only started 7 month ago to take 1 mg finasteride daily, but it has thin my hair considerably because of the boost of scalp tesoterone it caused i think. I tried to add different antiandrogen topically such as ru58841 to tackle the rise in T (had to stop due to chest pain , shortness of breath), i used now topical cb0301 30mg/day but it is not enough powerful so it doesn't do sh*t. I am going to try topical bicalutamide now soon as it is a stronger AA and i think we have to fight testoerone as well.
Besides finasteride + cb0301 i don't take any supplement and it didn't stop my shedding at all.

I am curious to know about how much you lose hair per day, what regimen are you on, it seems you use minoxidil, dit it worked on you ? and how you manage to apply it all over your head ?

Also can you share if anything in your regimen has improved your situation so far or make it worse. Would be great to share info

You can send me a message privately as well.

Looking forward helping each other to solve that sh*t.

Best regard

 

[camille leprevost]

Hello, just to recap, I am a man and have DUPA hair loss (or female pattern hair loss), diffuse hair loss and thinning (back, sides and top) which started 3 years ago after an episode in my life where my alimentation was very bad and had nutrient deficiency for sure. After fixing my alimentation properly my hair are still shedding and thinning all over.

Since 8 month i only take 1mg finasteride / day (no reduction on my hair loss), cb0301 30mg topicaly with no reduction on my hair loss, Biotin (10mg/day), spearmint tea (4 cup/day to reduce free testosterone), Flaxseed (30 g/day to reduce testosterone)

Here is a complete blood test that I have done 3 weeks ago. It would be great if some of you may highlight some issue in it and maybe propose corrective action as he might help others with similar hair loss.

From my perspective, I think I have low zinc, low vitamin d, high prolactin level, high cortisol level and maybe iron deficiency as we can have it according to study even with normal level of blood iron.

BLOOD TEST of the 04.12.2020

Vitamin B12 : 812 ng/l (197-771)
Vitamin A : 0.5 mg/l (0.1-1)

IONIC BALANCE

Sodium : 139 mmol/l (136-145)
Potassium : 4 mmol/l (3.5-4.5)

PROTEIN

Albumin : 47 g/l (40-49)

RENAL FUNCTION

Urea : 46 mg/dl (17-48)
Creatinine : 0.94 mg/dl ( 0.7-1.2)
DFG (CKD-EPI) >90 mL/min/1.73m^2

LIVER/PANCREAS

AST(GOT) : 16 UI/L (<40)
ALT(GPT) : 10 UI/L (<41)
alkaline phosphatase : 55 UI/L (40-129)
Gamma GT : 10 UI/L (10-71)
LDH : 178 UI/L (135-225)
Biribulin total : 0.8 mg/dl (<1.2)
Biribulin conjugated : 0.3 mg/dl (<0.2)

CARDIOVASCULAR RISK FACTOR

Triglyceride : 68 mg/dl (<150)

CARBOHYDRATE METABOLISM

Fasting glucose level : 96 mg/dl (70-100)
Insulin : 39.7 mg/dl (17.8-173)
Index HOMA1-IR : 1.4 pmol/l (<2.4)

TYROID

TSH : 1.35 mu/l (0.27-4.20)
T4 libre : 17.8 pmol/l (12-22)

ADRENAL GLAND

Cortisol (morning test) : 480 nmol/l (166-507)

CALCIUMPHOSPHATE METABOLISM

Bioactive PTH (3nd gen) 25.5 ng/l < 49
25 OH vitamin D : 14.8 μg/l (30-80)

ENDOCRINOLOGY

Total prolactin : 18.2 μg/l (4-15.2)
Bioactive prolactin : 14.9 μg/l (3-11.6)
LH : 5.8 UI/L (1.7-8.6)
FSH : 1.9 UI/L (1.5-12.4)
Oestradiol : 30 ng/l (25-52)
Progesterone : 0.24 μg/l < (0.15
17OH-Progesterone : 3 ng/ml (0.9-3.4)
total Testosterone : 20.80 nmol/l (8.64-29)
Testosterone free: 509.1 pmol/l (260-740)
Androstanediol glucoronide 2.8 nmol/l (4-75)
Delta 4 androstenedione : 1.4 ng/ml (0.1-3)
DHEA-S : 4.72 μmol/l (4.34 – 12.20)
SHBG : 24 nmol/l (18.3-54.1)
DHT : I don’t have the result yet

TOXICOLOGY

Zinc : 72 μg/dl (80-120)

BLOOD

Haemoglobin : 16.6 g/dl (13-18)
Red blood cell : 5.40 10^6/μl (4.40-5.90)
Hematocrit : 45.5% (40-53)
mean corpuscular volume : 84 fL (80-100)
mean corpuscular HB : 30.6 pg (26-34)
mean corpuscular haemoglobin concentration : 36.5 g/dl (31-35)
anisocytose indice : 12% (11.5-13.4)
platelet : 208 10^3/ μl (150- 440)
mean platelet volume : 10.1 fL (8.9-12.9)
white blood cell : 7.16 10^3/ μl (3.5-11)
neutrophiles : 62.1% (40-75)
neutrophiles (absolute): 4.44 10^3/ μl (1.5-6.7)
Lymphocytes : 25.4% (20-45)
Lymphocytes (absolute) : 1.82 10^3/ μl (1.2 – 3.5)
Monocytes : 10.6 % (2-10)
Monocytes (absolute) : 0.76 10^3/ μl (0.2 - 1)
Eosinophiles : 1.5% (2-10)
Eosinophiles (absolute) : 0.11 10^3/ μl (<0.4)
Basophiles : 0.4% (0-1)
Basophiles (absolute) : 0.03 10^3/ μl (<0.1)

INFLAMMATORY SYNDROM

Crp : <0.5 mg/dl (<5)

ANEMIA

Iron : 134 μg /dl (65-175)
Transferrin : 216 mg/dl (215 – 365)
Transferrin saturation : 44% (16-44)
Ferritin : 120 μg/l (30-300)
Folic acid : 4.8 μg/l (>4.6)
Folic acid erytrocytaire : 754 μg/l GR (523-1257)

 

[camille leprevost]

hello there,

i just readed an interesting post Propecia and 5AR1 | HairLossTalk Forums toward finasteride, as we know fina block only type 2 of the 5ar enzyme. However type 1 5ar is present on the skin/ scalp and hair. Then i think it is possible that the increase of T that fina causes when it block 5ar2 might increase the activity of the 5ar type 1 which is present in your hair an skin, that's could explain why fina did't have any effect on dupa hairloss and maybe caused also an increase of acne for some of us. Maybe us duppa sufferer can be fucked up equally by 5ar1 and 5ar2

Thats why i am asking if any dupa sufferer out there tried dutasteride or topical dutasteride sell by minoxidil max. Dutasteride seems to block type 1 and 2 of 5ar.

I found one post who claim to have stopped his hairloss with duta :
Was dutasteride the right call for someone with DUPA? | HairLossTalk Forums

any thought so far ?