All you need to stimulate growth in balding areas is estradiol and an androgen inhibitor.
f*** all this noise bro. use dutasteride 0.5, oral minoxidil, and then an anti androgen like ru58841 or pyrilutamide. and stick with it for the rest of your life.
why 5-alpha reductase and Pyrilutamide together?
because dht is not the only androgen that causes hair loss, and regardless dutasteride does not block out all scalp dht. so a topical anti androgen is necessary. if youre only going to do two things, a 5ar and topical anti androgen should be those two things.
What else except dht could cause to hair loss based androgen alopecia?
I’ve gone back to taking spironolactone—it’s the best medication for restoring hair growth in the androgen-sensitive areas. My standard dose is 25 mg, taken after breakfast. I’ve recently changed my dosing schedule, moving it to the morning and combining it with 1 mg of estradiol gel. Previously, I used to take spironolactone in the evening after dinner, which upset my stomach. I stopped taking finasteride because it triggered ringing in the inner ear—so-called tinnitus. It’s a rare side effect, but it does happen.
0.6% is the estradiol concentration in 0.75 mg of gel. I buy it at any pharmacy.
I used 3 mg in 2019–2020; that gave me 800–850 pmol—roughly 200 pg—meaning 1 mg yielded 50–60 pg. In terms of blood concentrations, it delivers exactly what the studies claim.
Apply to clean skin—specifically the shoulders, forearms, and arms (excluding the hands).
From 2019 to 2020, I was taking 3 mg of Estrogel; I had a blood test for estradiol, and 9 hours later, my estradiol level was 850 pmol/L and my testosterone level was 0.
