Adding dutasteride in combo with proscar?

CCS

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17% of men continue to lose hair while on propecia, and the average guy continues to lose hair after the first 2 years. So I think it is possible people with bad genetics will continue to thin, but probably not at the agressive rate they had been. more likely just like the general population thins as they age.

power sam says he had a huge shed in his temples after starting avodart 7x per day, and it went away after switching to 0.5mg/day finasteride, though it did not grow back.
 
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gotcha. so assuming the dutasteride is real and my genetics are not really awful then i should just thin as the average male does in this country, like maybe norwood 2 by 45 or so? do you happen to have an idea on what the absolute average male in this country's hair loss pattern looks like over their lifetime? do average guys hit norwood 2 around age 45-50 or is it worse or better than that?

i know theres no way to tell but just looking for some estimates. cause i gotta think that inhibiting 95% of DHT Is a lot better than 80% if my genetics are worse than average. Every little bit helps.

and is it necessarily awful that im balding early? as i mentioned in other posts, my dad's side of the family gave me the hair loss, and my dad, although he started losing at 18, is only like a norwood 4 right now at age 50, and hes been that way for about 5 years without ever taking any hair loss drugs. so i gotta assume with all this dht inhibition that i will be able to stay a couple norwoods ahead of him on the pace.

also one last stupid question if i may. by getting on the dutasteride now, i'm not losing any effectiveness or whatever compared to getting it on it 10 years from now, right? like propecia it won't lose its effectiveness so getting on earlier is better?

thanks:D

thanks[/b]
 

Felk

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JayMan said:
hey felk,

id do almost everything i could to keep my hair, and to be honest, if this dutasteride+proscar combo prevents me from losing any more hair, which i think i will, im willing to run the risk of some nasty effects down the road.

Its exactly this attitude which worries me, as many people do themselves damage this way. Later on, im sure you may regret it if you are unlucky enough to get "nasty effects."

However i'm glad you asked a professional, even if he was a hair transplant surgeon and not a doctor.

As long as you're aware of it its fine, your decision of course. I just want people to be aware of these things.

I was also hoping there might have been a study out there on taking both finasteride and dutasteride which i had missed seeing, but sadly no.
 
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Felk said:
However i'm glad you asked a professional, even if he was a hair transplant surgeon and not a doctor.

Felk, hair transplant surgeons ARE doctors. They're trained surgeons and they all went to medical school just like dermatologists. I didn't ask that guy though. I just pasted the thing from another message board to show that a hair transplant surgeon said it was fine. I also asked Bryan and he foresaw no problems with it.

Felk said:
I was also hoping there might have been a study out there on taking both finasteride and dutasteride which i had missed seeing, but sadly no.

I don't think there would be nearly enough demand or interest to conduct a study like that. The only reason to take both as college said is if you doubt the authenticity of the drugs. I would switch right now to dutas and dump the proscar if I was 100% sure the dutas is real. As the hair transplant surgeon said, the proscar just mimics the work of the dutas.
 

Felk

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Oh you know what i mean, hair transplant surgeons are also salesmen, and have the accompanying set of motives, etc. Same can be said about some hair loss doctors i guess - just see Dr Lee and his whole azelaic acid thing :p
 

CCS

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JayMan,

starting sooner is better than later. You will NOT lose effectiveness by starting early. You WILL lose irreplaceable hair by starting 10 years later.

As for hair transplant doctors, they want you on propecia so you don't end up looking like a freak and making people think hair transplant is not a viable option, but they do not want to tell you about SODs, because if you regrow your hair, you won't need hair transplant.

I decided to do dutas every three days. I think 3x per week is better, but I decided to have a 6 day workout schedule and do nizoral every three days and NANO on the two off days, so it is just easier to schedule it if I do the dutas every 3 days. It is almost the same, the important part of a regimen is it must be easy to remember and stick to in a habit and should not interfer with your life. So if i just get everything sincronized, it will be easy. Maybe I'll pop an extra pill every month and put one in my cream.
 
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thanks college.

if my genetics start to really suck in the future and i do gradually lose my hair then i may need stuff like folligen to grow the hair back, right?
 

CCS

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yeah, it would be a good choice, though even spironolactone might do it if you only lost a little.
 
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collegechemistrystudent said:
yeah, it would be a good choice, though even spironolactone might do it if you only lost a little.


i thought spironolactone is just a topical dht inhibitor. how does it grow hair?

what i don't get is this- i know people who are on spironolactone+ avodart which to me would seem like it would suppress close to 100% dht if not 100%. And some of them are still losing hair. how is this possible?

thanks.
 

CCS

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The term "DHT inhibitor" is ambigous. It is better to say "5ar blocker" or "androgen receptor blocker" so it is clear whether the production or binding of DHT is being blocked.

I don't know why these men continue to loose hair, but that is not 100% of DHT blcked.
 
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it's gotta be pretty close right? with avodart knocking out 95% of the type 2 and then spironolactone blocking the binding at the androgen receptors?
 

CCS

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I'd guess that would push it to 98%, though more DHT would leak out of sebum glands when they have nothing to bind to, which would increase the amount leaking into the follicle, though maybe not after steady state.
If spironolactone could stop 4 out of 5 of the last 5%, it would probably inhibit 80% of binding by itself, and work better than propecia, which it does not. Maybe RU in the right vehicle would.
 
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thanks

i understand now thanks. so whats your guess on a percentage of people who can maintain their current level of hair once they have started dutasteride. By maintain i mean thin no more so than the average male in this country from that point on.
 

TAINTED-MEAT

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I think that even with dutasteride, you would eventually go bald if you started balding at a young age.
 

CCS

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many guys who go bald early have agressive hair loss and probably make up the majority of the 17% of propecia non-regrowers. I personally just saw a stopping or drastic slowing of hair loss on propecia. Since you are just a Norwood 1.5, I don't think your hair loss is as agressive as mine. dutasteride should work for you.
 
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hey college,

as ive said before my closest blood relative balding is my dad, and hes a nw4a at age 50, and not progressing. if i can keep mine to a nw2 at 50 ill be happy.

out of curiosity, where do you think the avg US male is at 30, 40, and 50 is on the norwood scale? that includs all males, male pattern baldness and non-MBP.

or if this is a better way to answer, at what average age do you think the avg male in this country hits NW2, etc. Do most ever hit NW3 at any age?

i know there's no data on it that i know of, but was just looking for some thoughts.

thanks.
 

Goingat20

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im worried about using dutasteride daily because of the 5AR1 in the brain issue. Im thinking of taking dutasteride twice a week and finasteride 5 days. Problem is i tried finasteride before and it didnt seem to work... Any suggestions?
 

Felk

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There is no reason to take finasteride along with dutasteride, because finasteride does nothing to improve on dutasteride, apparently dutasteride is simply too powerful, finasteride just can't compete with it. I think this is also true at a lower dose, but ask CCS or Bryan (who were saying this)

However it does say on the avodart instructions that you "can NOT take it with finasteride" or something. I don't know if it's dangerous or just being over cautious.

I think the main reason CCS was telling people to do it was in case their finasteride/dutasteride was fake, the other would back it up.

How is your hair going anyway? haven't heard from you in a while!
 

Goingat20

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Unfortunately, hair is getting worse. Ive stopped flutamide (cant afford to take risks with systemic absorption), and also stopped spironolactone 2% lotion as i read in an article that lotion doesnt really work. im currently using dutasteride (few times a week), along with prox-n (daily) and minoxidil (1-2 a day). Im thinking of using either proxiphen, revivogen, spironolactone cream or maybe even RU ( if me and ccs can get a few more people we will be getting it). How are things going with you, hows the proxiphen? I remember that you have curly long hair, are you able to apply it well? my hair is also curely and long. Any positive results?
 
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