Time of day doesn't matter, though I always took it in the morning hours during the first few months because there *is* some adjusting your body has to do once you start on it.
The cool thing about Propecia is you can't even tell you've taken it after you take it. Most pills you can at least feel in your stomach, or feel a change, etc within an hour or two. You won't notice or feel a thing after taking it.
After about a week on it you may feel a little disconglomerated, or you may feel nothing. Most feel nothing. Depends on how sensitive you are to hormonal changes. At the very worst you will just need to take care of yourself and get good rest... then it will go away.
As for working out, it should actually begin to enhance your workouts for awhile with the temporary increase in testosterone.
The big concern with new propecia users is that you must be on Nizoral shampoo every 3 days and you must expect to shed like mad for the first few months, and plan to ride it out. If it doesn't happen, great. If it does though, you will be sorely tempted to drop treatment. Don't. Stick with it.
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