2% Ketoconazole cream?

Megadeth

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I use Nizoral 2% shampoo about 2-3 times a week. I saw a few ebay sellers selling 2% ketoconazole cream. Will this work as a leave in treatment?
 

slurms mackenzie

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I've started using (as of yesterday) a 2% Keto cream, my scalp just can't handle the shamppo, there was a Japanese study done using it, the results were impressive.

http://www.hairsite.com/hair-loss/forum ... nswer.html

The bonus for me is that the cream (daktarin gold) also contains polysorbate 80 which may have an additional benefit.

The cream in the study was put on after shampooing.

This 'frees up' a shampoo to use, so I'll be moving to Alpecin Double Effect. The caffeine is a secondary consideration, the main reason is i want to try a piroctone olamine shampoo.

International Journal of Cosmetic Science. 24(5):249-256, October 2002.
Pierard-Franchimont, C.; Goffin, V.; Henry, F.; Uhoda, I.; Braham, C.; Pierard, G. E.
Abstract:
Synopsis: Hair shedding and hair thinning have been reported to be affected by dandruff and seborrhoeic dermatitis. The present study was conducted in 150 men presenting with telogen effluvium related to androgenic alopecia associated with dandruff. They were randomly allocated to three groups receiving each one of the three shampoos in the market containing either 1% ketoconazole (KTZ), 1% piroctone olamine (PTO) or 1% zinc pyrithione (ZPT). Shampoos had to be used 2-3 times a week for 6 months. Hair shedding during shampoo was evaluated semiquantitatively. Hair density on the vertex was evaluated on photographs using a Dermaphot. Trichograms were used for determining the anagen hair percentage and the mean proximal hair shaft diameter using computerized image analysis. The sebum excretion rate (SER, [mu]g cm-2 h-1) was also measured using a Sebumeter(R).

The three treatments cleared pruritus and dandruff rapidly. At end point, hair density was unchanged, although hair shedding was decreased (KTZ: -17.3%, PTO: -16.5%, ZPT: -10.1%) and the anagen hair percentage was increased (KTZ: 4.9%, PTO: 7.9%, ZPT: 6.8%). The effect on the mean hair shaft diameter was contrasted between the three groups of volunteers (KTZ: 5.4%, PTO: 7.7%, ZPT: -2.2%). In conclusion, telogen effluvium was controlled by KTZ, PTO and ZPT shampoos at 1% concentration. In addition, KTZ and PTO increased the mean hair shaft thickness while discretely decreasing the sebum output at the skin surface.

I don't fully know the reason why Keto shampoos became the shampoo of choice, although i'm sure there was a reason, anyway if you can't stand Nizoral, I think the PO shampoos offer a good alternative.

I don't use minoxidil, so that after shampoo window is conviniently free
 

smitysmity

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The cream is more effective than the shampoo. I just purchased the 2% Cream as well online. The Shampoo does very nicely in my hair and I am tempted to use it 7 times a week.

It's pretty ridiculous that you can't buy 2% Cream over the counter in the United States.
 

squeegee

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smitysmity said:
The cream is more effective than the shampoo. I just purchased the 2% Cream as well online. The Shampoo does very nicely in my hair and I am tempted to use it 7 times a week.

It's pretty ridiculous that you can't buy 2% Cream over the counter in the United States.


Bought the cream from egay?
 

rwhairlosstalk

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I tried the cream and it did absolutely nothing for me.

But make me shed more. But maybe it will help you.
 
J

jonson

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Rw maybe it was shedding of beginning an treatment..
I also want to use the cream.. Is it good dht blocker?
 

Einstein

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smitysmity said:
The cream is more effective than the shampoo. I just purchased the 2% Cream as well online. The Shampoo does very nicely in my hair and I am tempted to use it 7 times a week.

It's pretty ridiculous that you can't buy 2% Cream over the counter in the United States.

hmm here in canada we can buy 2% shampoo over the counter, but now I wonder if we can buy 2% cream as well. Now you got me thinking...
 
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