Update regarding the phase 2a trials:
"Evaluation of efficacy by measurement of non-vellus Target Area Hair Count (TAHC) showed mean changes from baseline of 24.3 hairs with the high label strength (0.02%) and 20.3 hairs with the low label strength (0.0025%) topical solution, compared to 14.0...
These are the phase 2 results that Kintor shared for Pyrilutamide:
Placebo BID was around 7 TAHC cm2
5mg BID was around 22 TAHC cm2
22 - 7 = 15 TAHC cm2 when comparing change versus placebo at 6 months.
What would be more interesting in my opinion is to know whether Pyrilutamide looses...
Are we sure that phase II is completed for TDM-105975?
The clinical trials gov website says it's still in the recruiting stage: https://clinicaltrials.gov/study/NCT05802173
I'd like to apologise for not sharing my MSM experience much earlier, but better late than never..
Here is a little timeline of what I documented back between late 2021 and 2022 of my MSM experience.
7th December 2021 - I started taking 11g MSM daily (10 tablets per day).
8th January 2022 - I...
Apologise for the slow updates...
Last update from TechnoDerma was they started Phase 2 dosing earlier this year: https://www.clinicaltrialsarena.com/news/technoderma-dosing-phase-ii-study-Androgenetic Alopecia/
Hoping for some positive phase 2 results circa 2024.
There’s a new study for some analogues of TDM.
“Results: The TDM group showed early induction of anagen. 857, 782, and 276 differentially expressed genes were identified between 3 groups. As a critical DEG in group TDM, Pclaf was positively related to the motivation of Wnt/beta-catenin and...
KX-826 / Pyrilutamide now has a CAS number: https://www.chemicalbook.com/Search_EN.aspx?keyword=1272719-00-2&start=0
You can also see here it's been synthesized for reference purposes by two chinese labs already:
https://www.chemicalbook.com/ProductList_En.aspx?cbn=CB88252856
Hey all,
Small update:
There are now exactly 40 people who purchased UT-34.
19 people have started dosing and the doses range from 0.1 - 0.5% and the majority of users have been dosing for about 2-3 weeks now.
No one has reported any side effects as of yet.
Whilst some users have mentioned...
I would like to remind everyone not to get overexcited, as there was another cosmetic a few years ago named "Brotzu's lotion" and we all know how that went...
That being said, this product actually has 2 registered clinical trials and a published study so it's already massively up on Brotzu /...
Efficacy isn't massively spectular no, but I think the point here is:
1) It's stackable with 5ARIs and other anti-androgens for extra protection
2) It's only a weekly treatment
3) It's a cosmetic which means it doesn't have to go through 3 phases of clinical trials so hopefully we get our hands...
I just came across this new study too.
At 24 weeks the high dose (5mg/ml) AR68 maintained just above baseline in both hair density and total hair count, the pictures in my opinion are not massively impressive but technically it did maintain at 24 weeks.
The most interesting thing for me...