Recent content by jondoeuk

  1. J

    Good addition to big 3 plus pyrilutamide?

    RU has no published human data.
  2. J

    Oral bicalutamide Log - HemingwayTheMercenary

    Talk about nuclear stack! Fluridil is a topical antagonist of the androgen receptor. Fluridil binds to the androgen receptor with approximately a 9-15-fold higher affinity than bicalutamide. That said, pyrilutamide has an even higher affinity and a lot more clinical data...
  3. J

    Pyrilutamide (KX-826) 1.0% and 0.5%

    ''The WCHR is the the most influential academic conference in the global hair research field. Held biennially, it provides participants with a unique opportunity to delve into the outcomes of recent clinical trials and experimental studies. Two important clinical studies are as follows. (i)...
  4. J

    Pyrilutamide (KX-826) 1.0% and 0.5%

    A 24-week period provides enough time to spot statistical changes in hair density. After the 24-week period ends, trial participants can be given the medication to evaluate long-term results. Kintor presented long-term results https://en.kintor.com.cn/news_details/9.html
  5. J

    Pyrilutamide (KX-826) 1.0% and 0.5%

    Good news ''The Pivotal Clinical Trial is a multi-center, randomized, double-blind, vehicle-controlled phase II/III study with adaptive designs to evaluate the efficacy and safety of KX-826 tincture 1.0% and 0.5% for the topical treatment of male adults with Androgenetic Alopecia in China. The Pivotal Clinical...
  6. J

    New topical anti androgen and starting TRT

    Pyrilutamide is a topical nonsteroidal antiandrogen developed by Suzhou Kintor Pharma, a subsidiary of Kintor Pharma Limited. In addition to its ongoing clinical development, it has been introduced to the market as a cosmetic under the brand name Koshine...
  7. J

    New topical anti androgen and starting TRT

    That's the grey market for you! Cosmo Pharma should release the six month phase three results this quarter, and twelve month results in the first half of 2026. If all goes to plan they expect to receive FDA approval in late 2027 and will release it soon after. The market research that was done...
  8. J

    Fluridil (Eucapil)

    Pyrilutamide is sold (by Kintor Pharma) under the brand name Koshine https://www.koshinemall.com?sca_ref=7290283.HUfjZVF7fCV5W
  9. J

    Fluridil (Eucapil)

    Keep us updated. For pyrilutamide, patents. As for fluridil, a search on certain sites for topilutamide. I will look for the binding affinity of topical spironolactone when I get time. I currently take oral finasteride, but plan to add (topical) liposomal dutasteride.
  10. J

    Pyrilutamide (KX-826) 1.0% and 0.5%

    Long-term (52-week trial) data. The results demonstrated excellent safety and efficacy. Key highlights: 46% of patients saw a ≥10 hairs/cm2 change in total area hair count (TAHC) from baseline. 20% of patients saw a ≥20 hairs/cm2 change in TAHC. This trial involved a total of 16 clinical...
  11. J

    Does hair growth oil work long-term?

    Hair growth oil?
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