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Yes, absolutely right, but it binds last of all—when there is neither testosterone nor DHT left in the blood. This is a natural...

So what are you suggest? Estradiol Gel/sublingual or oral? By the way, SHBG binds estrogen too.

Absolutely all androgens are harmful to hair—and it’s not just DHT. Using 1–2 mg of estradiol gel won’t cause a man to turn into a...

Absolutely all androgens are harmful to hair—and it’s not just DHT. Using 1–2 mg of estradiol gel won’t cause a man to turn into a...

Applying estradiol gel to the scalp will clearly have no effect on hepatic SHBG.

Applying estradiol gel to the skin of the hands, thighs, or buttocks affects the liver, but only over the long term; oral tablets, on...

That right but in another place like arms, How it work without pass the liver like you said?

Applying estradiol gel to the skin of the arms, thighs, or buttocks also raises SHBG levels—though over the long term and not as sharply...

You said that Estrogel helped you in another posts.

Patient Profile Patient Name: Prashant More Gender: Male Age Group: Adult Male Procedure: BIO-FUE Hair Transplant Total Grafts: 4,000...

It works for regular Androgenetic Alopecia but for the unlucky few who have DUPA the working theory rn is diffuse alopecia areata (aka alopecia areata...

So what do you say that estradiol sublingual or Estrogel or any method that pass the liver doing nothing?

From what ive read on people with dupa they’re extremely nonresponsive to dht blockers, there’s people on the dupa subreddit who have...

I mean, it's better to push oral duta to 2,5mg or continue in 0,5mg duta but using a topical spironolactone in the scalp (or other...

Can anyone help me? I took finasteride in 2021 to prevent hairloss. I had a massive upregulation caused by it (massive continuous hair shedding...