Why topical DHT inhibitor should be considered along w/ finasteride

[ripple-effect]

Got this interesting tid bit off of an interview w/ Revivo creators:

Q: The very fact that you would produce a topical DHT inhibitor implies that you don't feel that blood levels of DHT are significant in balding. Can you justify this point of view or provide evidence to support it?

A: The blood levels of DHT may play a minor role in Androgenetic Alopecia but it is the locally produced DHT which plays the major role. If you look at any physiology text book (such as Guyton's Medical Physiology) you can see that the majority of DHT production takes place at the site where it exerts its effects. Also there is a high concentration of type 2 isoenzyme within the hair follicle itself and a higher concentration of the type 1 form within the scalp and sebaceous glands which feed into the hair follicle. Together they can produce more DHT locally than what blood brings to the hair follicle. Also most researchers now believe that it is the locally produced DHT that is involved in Androgenetic Alopecia rather than the circulatory DHT. Finally there is new evidence about effectiveness of topical inhibition of DHT on hair growth by Dr. Christiano which provides support for this theory.

http://www.hairlosstalk.com/productrevi ... iew.htm#12

 

[KielMcK]

I haven't heard of anyone really that has done that well on revivo tho. I agree that topical dht inhibitors are the way to go along side finasteride. but revivo doesn't sound like the answer to me.

 

[RaginDemon]

I haven't heard of anyone really that has done that well on revivo tho. I agree that topical dht inhibitors are the way to go along side finasteride. but revivo doesn't sound like the answer to me.

I think I want to give topical spironolactone a go.

 

[ripple-effect]

I haven't heard of anyone really that has done that well on revivo tho. I agree that topical dht inhibitors are the way to go along side finasteride. but revivo doesn't sound like the answer to me.

Revivo is usually successful in maintaining what you have. I wish I figured this out sooner, but I'm pretty sure Revivogen is a very legit product. It didn't sound like the answer to me either, at first, but now it's starting to make more and more sense to me (maybe cause I'm running out of popular options....lol). I still have alot of hair left and I'd be satisfied if I could just keep my hair from continuing downward.

I was just confused about the reviews of this product at first because some would give it pretty decent reviews and then others would completely confuse me by saying it's a complete scam b/c they didn't experience regrowth when it's mainly supposed to maintain or they would complain about the smell of the product when I believe it's worth it as long as it does the job. I'm not saying it works for everyone, according to their site 88% are successful in maintaining and/or regrowth. I don't know if it will work for me, but I'm just hoping it will.

I also think these complaints are directed to the old version of Revivo....I think the new formula was improved w/ stronger growth stimulants + a better scent.

 

[CCS]

finasteride inhibits DHT production locally as well as systemically. So revivogen is not stronger. But it does let you lower production more without lowering systemic levels. Topical spironolactone also helps locally, but in a different way.

since Avodart is no stronger than proscar at the 1 year mark, I doubt that all this androgen suppression is needed. But I do suspect that GLA might not be produced by aged skin enough, and restoring GLA locally could help hair loss in other ways besides 5ar inhibition.

 

[jh]

I haven't heard of anyone really that has done that well on revivo tho. I agree that topical dht inhibitors are the way to go along side finasteride. but revivo doesn't sound like the answer to me.

Someone seems to say this every couple weeks. Look through posts of long-term revivogen users - including the admin of this very website - and you'll find positive reviews.

I think many people jump from product to product, giving each a couple months. When they don't see massive regrowth they complain the products don't work and move on to something else.

 

[retropunk]

finasteride inhibits DHT production locally as well as systemically. So revivogen is not stronger. But it does let you lower production more without lowering systemic levels. Topical spironolactone also helps locally, but in a different way.

since Avodart is no stronger than proscar at the 1 year mark, I doubt that all this androgen suppression is needed. But I do suspect that GLA might not be produced by aged skin enough, and restoring GLA locally could help hair loss in other ways besides 5ar inhibition.

CCS,

do you know of any studies that actually show Revivogen being used in conjunction with Propecia? Revivogen seems to have a trail results page, but there's no independent review or anything.

Although, if someone were to want to use Revivogen because Propecia or Avodart gives them side effects, then they should use it. Worse thing would be dermatitis.

 

[ripple-effect]

I plan on using Revivo w/ Finasteride when my Revivo gets here in a few days.

 

[ripple-effect]

finasteride inhibits DHT production locally as well as systemically. So revivogen is not stronger. But it does let you lower production more without lowering systemic levels. Topical spironolactone also helps locally, but in a different way.

since Avodart is no stronger than proscar at the 1 year mark, I doubt that all this androgen suppression is needed. But I do suspect that GLA might not be produced by aged skin enough, and restoring GLA locally could help hair loss in other ways besides 5ar inhibition.

What does it matter if the DHT isn't inhibited systematically? Finasteride inhibits systematically b/c the drug cannot be directed towards the target sites otherwise. It's through systemic inhibition that the drug tries to achieve local inhibition. It doesn't matter which one is "stronger" or not, what matters is what works and what works best for you. The point is you are trying to save the hair on top of your head and what matters is blocking the DHT locally. Revivo blocks both types of 5-alpha reductase enzymes from 90 to 98% locally while finasteride only blocks type II.