what does start the hairloss?

asm

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Okay.

We know male pattern baldness is due to hormones and genes. But why doesn't balding start for everybody at the same age? Even if the answer is hereditary, what pushes your body at certain moment to fight against your hair?

Knowing this may help figure out what accelerates male pattern baldness and probably can show a way out of this mess.
 
G

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You can ask why someone get's cancer at 20 and not at 50, or why does someone get cancer at 50 and not at 30 or 40.

These are the age old questions. One thing is for sure though. Most people will start to bald around the same time. The speed of loss is just purley on how your body works. Everyone is different. It can stop and start at any time at any point in your life....

It's very complicated...
 

asm

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That was my stupid question... :)

But I still have hesitations about... It is said nearly 50% of 50's men start to bald. It means one of your grandfathers or grand-grandfathers or grand-grand-grandfathers, etc. had definetly hairloss. That means everyone has in his hereditary hairloss gene. Than all this theory about male pattern baldness sucks...

What do you think?
 
G

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I think when they discover what causes hairloss the sh*t will well and truly hit the fan...
 

asm

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But seriously speaking... If the male pattern baldness theory is exaggerated, then all we do to save hair can be nearly fake.

Surely, Propecia helps responders. But how do you know that it really blocks DHT? Did you see this DHT or how it should be blocked? You know nothing about it and our lack of infromation may be skilifully used by pharms!

Good luck, for those whom Propecia did or does help! But probably it did something that you can do without it to still maintain or regrowth. For example, breathing exercises, green tea or yoga :)

I'm talking it because I know a man who did stop hairloss and got some regrowth stopping to eat fats! Simultaneously, he started doing some activities (like simple jogging) and drink full barrels of green tea. No Propecia. No Minoxidil.

I don't apply to you, traxdata, trying to convince. Just want to tell what I think about all this, since there is too much conflicting info regarding male hairloss.

Asm
 

JayB

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Furthermore, I dont understand this. If you grow chest hair and facial hair, you obviously have DHT present in your body. Why in mid 20's or 30's does this suddenly cause your hair to fall out when youve had it floating in your body since high school....i know plenty of kids with a rug on their chests who had a full head of hair at 16, but then suddenly in their early 20s started losing hair. It doesnt make sense, why not at 16 when the DHT began to cause them to grow body hair.
 

iamnaked

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Well:
Firstly, the expression of a gene-controlled characteristic is not uniform in our species. Take the same gene in one person and a different person, the gene will be expressed more strongly in the one than the other. This is because there is a massive degreee of interdependence between genes and other genes.
This is why your brother can be balder/less bald than you at the same age.

Secondly, our cells change as they divide. For instance the cellular mitochondria responsible for energy generation shorten each time they do so. It is possible that after they have divided for a set number of times and the mitochondria are sufficiently short they become susceptible to the influence of DHT.
This explains why people start going bald after a period of time.
 

asm

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iamnaked said:
Well:
Firstly, the expression of a gene-controlled characteristic is not uniform in our species. Take the same gene in one person and a different person, the gene will be expressed more strongly in the one than the other. This is because there is a massive degreee of interdependence between genes and other genes.
This is why your brother can be balder/less bald than you at the same age.

Secondly, our cells change as they divide. For instance the cellular mitochondria responsible for energy generation shorten each time they do so. It is possible that after they have divided for a set number of times and the mitochondria are sufficiently short they become susceptible to the influence of DHT.
This explains why people start going bald after a period of time.

Genes - OK. Somehow partly I do believe in hereditary. But how can it be concerned with DHT and androgens?

My uncle has no body hair at all! And he's still thinning while he's 45. Where is DHT here? We are told DHT induces hair growth on arms, legs, back, etc.. There are many such examples.

I think somewhere in the world we can even find tweens - one with hairloss and another without. It's not only about genes, but it is also doubtful that the next best part is DHT.

We do believe in all this theory because we have been told! Mostly by pharms in such manner: "Yeh! It's all about DHT and it's blocking. Take our pill and everything is OK." But remember that phase 3 of Avodart trials has been cancelled (most popular opinion) due to someone at GSK who thinks it won't do much cash. All they care is cash.
 

arjun17

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male pattern baldness is caused not only by DHT, but also by sensitivity to it

I agree that DHT is there at full levels in our bodies immediately after completing puberty (age 16 on average - variation 13-19). But the hairloss is due to cumulative, not immediate effect of DHT (except in the very rapid, early onset, NW7-by-25 variety of male pattern baldness) Even non-balding guys do not lose their temples immediately after puberty at age 16 or 17, as some sites suggest "temple recession is a part of puberty" but lose them only after accumulated exposure to DHT for 5-10 yrs (most non-balding guys lose some of their temples anytime in their 20s, usually mid-to-late 20s) This is also why hairloss still continues even after "andropause" in men (around late 40s), although at a slower rate, because the sensitivity of the follicles increases somewhat to counteract the effect of less DHT production.
And it is true that a higher percentage of guys with lots of body hair tend to bald than those with moderate or little body hair. But this is not always true - there are exceptions. Take an example of two of my friends, both age 18. One has very little body hair , and does'nt need to shave yet , but in spite of this, he has receded a little at his temples. The other one is a hairy beast, with loads of chest hair, a strong-growing beard(it would not be excessive for him to shave twice a day) and even some back hair. But he has thick curly hair, and has'nt receded at all as of now.
Thus it is the sensitivity of the follicles to DHT, not the level of DHT itself, which is more important.
Cheers,
Arjun
 

asm

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Re: male pattern baldness is caused not only by DHT, but also by sensitivity t

arjun17 said:
Thus it is the sensitivity of the follicles to DHT, not the level of DHT itself, which is more important.

This means the dosage of finasteride should be selected individually for everyone. Like the dosage of Accutane for those who suffer from acne.
 
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