Topical Spironolactone

[Heatman]

Hello.
I am starting topical spironolactone 5% solution. Now I've read online something about a black box warning, and how spironolactone is associated with tumors and to avoid unnecessary use. This worries me, since the brain is the most sensitive part of the body. Is this not dangerous?

 

[Boondock]

That's the first I've heard of it. Can spironolactone penetrate into the blood vessels of your scalp? Possibly. But could it seep through your skull into your brain? Definitely not.