Topical finasteride/dudasteride

[luke77]

Hi guys,
I have stopped using finasteride/dutasteride due to side effects and don't plan on restarting it orally. I have a bunch of extra tabs sitting around that I'm not going to use, so I'm thinking that I might as well try to make a topical finasteride or dutasteride. I know there is not a whole lot of evidence to back up the efficacy of a topical finasteride or dutasteride, but the worst that's going to happen is that it won't work...so can anyone give me any guidelines how to make a topical? For instance, what kind of vehicle should I try using - ethyl alcohol or something like dermovan? I'm allergic to PPG so I can't use that in ethyl alcohol, but I was thinking that I could substitute water or glycerine if I can find some. Also, if anyone has used a topical finasteride or dutasteride, have you had any success?

If someone tells me how to make a topical I'll keep you guys informed as to how or whether it works.

Thanks,
Luke

 

[luke77]

Bump?

 

[Bryan]

The worst thing that could happen isn't that it simply wouldn't work; the worst thing is that it would be absorbed systemically to a significant extent, and cause the same side-effects that you got when you took the stuff orally.

I would avoid using water as part of a topical vehicle, because those drugs aren't soluble in water. Use as pure an ethanol as you can get, along with (perhaps) some pure glycerine.

Bryan

 

[luke77]

Thanks.

 

[Britannia]

Just take the stuff orally. Or use an established topical treatment - theres enough to choose from: Revivogen, spironolactone, Nizoral, Azelic Acid, Dr Lee's Minoxidil solutions with DHT blockers etc. Stop confusing matters.