Topical dutasteride?

[michael barry]

Hi guys,
They sell this stuff over at lipoxidil. I was wondering if anyone has tried it, had success with it?

 

[Britannia]

Topical dutasteride would be ineffective just like any attempted topical finasteride has proven to be. Try spironolactone.

 

[Boru]

Topical dutasteride would be ineffective just like any attempted topical finasteride has proven to be. Try spironolactone.

You don't know that for sure, it may be an experiment worth trying.
Boru

 

[michael barry]

I thought that topical finasteride was very well absorbed in the skin? Its why they tell pregnant women not to even handle the pills with their fingers? Have you seen any studies on topical finasteride? On dutasteride. I know its sold, but havent gotten any feedback from users. ......Interesting.

 

[Britannia]

Topical dutasteride would be ineffective just like any attempted topical finasteride has proven to be. Try spironolactone.

You don't know that for sure, it may be an experiment worth trying.
Boru

I pretty sure it wouldnt work. And if it did then it would be because the finasteride or dutasteride would be absorped systemically - so you might aswell just take it orally. If it were possible to produce an effective topical finasteride or dutasteride product then a large pharmaceutical company would have done it by now. If you wish to "experiment" rubbing this sh*t into your scalp then good for you.

 

[Britannia]

Topical dutasteride would be ineffective just like any attempted topical finasteride has proven to be. Try spironolactone.

You don't know that for sure, it may be an experiment worth trying.
Boru

I pretty sure it wouldnt work. And if it did then it would be because the finasteride or dutasteride would be absorped systemically - so you might aswell just take it orally. If it were possible to produce an effective topical finasteride or dutasteride product then a large pharmaceutical company would have done it by now. If you wish to "experiment" rubbing this sh*t into your scalp then good for you.

 

[Boru]

Topical dutasteride would be ineffective just like any attempted topical finasteride has proven to be. Try spironolactone.

You don't know that for sure, it may be an experiment worth trying.
Boru

I pretty sure it wouldnt work. And if it did then it would be because the finasteride or dutasteride would be absorped systemically - so you might aswell just take it orally. If it were possible to produce an effective topical finasteride or dutasteride product then a large pharmaceutical company would have done it by now. If you wish to "experiment" rubbing this $#iT into your scalp then good for you.

Yeah, like you know what you are talking about long time.

 

[michael barry]

Brittania,
Dutasteride is supposed to be extremely well absorbed in the skin. Thats why its in gel cap form.....so women cant be handling it and deform male fetus genitalia if they are preg.

Ingested dutasteride inhibits 58% of scalp DHT according to Glaxo-Smith Klien. It gets 98% of blood serum level of type two DHT and a high percentage of type one (but I forget exactly how much).

I personally am looking around for some who have tried it and see what they think. I dont write things off quickly, and I try not to make rash decisions on this stuff. If I find out it doesnt work topically from some users/experimental data.....believe me, I wont try it, cause I know it'll be a bit pricey.

 

[user30-06]

Ok guys, believe me or not, it sounds incredible but the evidence that topical dutas could be the final answer in topical therapy (I always suspected) is coming out. I just read an article from a Swiss ( my mother country) magazine which relates of o book written by a consumer (not a physician only a expert in chemistry) who find the way to totaly reverse his baldness with topical dutas in a not specify vehicle, with a daily local exposure of few minutes. The article says not hour of exposure (during night or day) but only few minutes during the shower. I know, it sounds incredible to me too, but the magazine is one of the most reliable in Switzerland. The book should be available in the next 2 o 3 weeks. I'll keep you update (I'll fly to Switzerland next week).

 

[Boru]

Ok guys, believe me or not, it sounds incredible but the evidence that topical dutas could be the final answer in topical therapy (I always suspected) is coming out. I just read an article from a Swiss ( my mother country) magazine which relates of o book written by a consumer (not a physician only a expert in chemistry) who find the way to totaly reverse his baldness with topical dutas in a not specify vehicle, with a daily local exposure of few minutes. The article says not hour of exposure (during night or day) but only few minutes during the shower. I know, it sounds incredible to me too, but the magazine is one of the most reliable in Switzerland. The book should be available in the next 2 o 3 weeks. I'll keep you update (I'll fly to Switzerland next week).

Well said. We just need to know how to mix it. I see you are new here. Have you been a researcher contributer elsewhere? In the meantime, finasteride etc. is working for me, so the prospects for a topical dutasteride are exciting.
Boru

 

[Britannia]

My belief remains that if a topical preperation of dutasteride was a possible effective male pattern baldness treatment, then GKS would have developed this option.
They didnt for whatever reason - ineffective? Dangerous? Impractical?
Or ridiculously expensive. If you need to apply 1ml of 0.5mg Dutateride twice a day everyday then you will find your regeime bursting the £1000 a month line.

 

[michael barry]

Yes Brittania,
the cost is the major drawback with dutasteride. It would only be necessary once a day though as dutasteride last a long time in the body (much longer than finas). Thats why some people take one 3.5 g of avodart a WEEK.

Ive wondered why GKS didnt develop it either. It is sold at liopoxidil.com topically. I was fishin' for users to see if they were happy with the results. Doesnt seem like there are any users.

Only way to find out stuff is to look and ask. I always remember that. : )

 

[powersam]

3 or 4 studies were done on topical finasteride, but they had such widely varying results that no conclusion can really be drawn from them. Some had good results with little systemic absorption while another would show exactly the opposite. a topical inhibitor of dutasterides strength would be great but i cant see how it could possibly not be systemically absorbed. maybe they could try something like the eucapil people and somehow make it degrade in water.

 

[iamnaked]

My belief remains that if a topical preperation of dutasteride was a possible effective male pattern baldness treatment, then GKS would have developed this option.
They didnt for whatever reason - ineffective? Dangerous? Impractical?
Or ridiculously expensive. If you need to apply 1ml of 0.5mg Dutateride twice a day everyday then you will find your regeime bursting the £1000 a month line.

Clinical trials are hideously expensive. That's why finasteride and minoxidil aren't approved for the front of the head, even though there is very strong anecdotal evidence to suggest that they can help there too.

I would be willing to approach the topical dutasteride idea with an open mind. Its relative expense indicates that not many would have tried it yet, and thus it's not a dead cert that it's useless.

Your estimate of £1000 a month is very wrong as well. I pay 1$ a pill for my dutasteride, which makes $60 a month, or about £40. (perhaps you meant 1000 a year)

 

[pratc]

This thread is over eight months old. Has anyone got any positive or negative 'results' for topical dutasteride?

 

[Phillip]

Topical dutasteride would be ineffective just like any attempted topical finasteride has proven to be. Try spironolactone.

You don't know that for sure, it may be an experiment worth trying.
Boru

I pretty sure it wouldnt work. And if it did then it would be because the finasteride or dutasteride would be absorped systemically - so you might aswell just take it orally. If it were possible to produce an effective topical finasteride or dutasteride product then a large pharmaceutical company would have done it by now. If you wish to "experiment" rubbing this $#iT into your scalp then good for you.

Its easy to figure out if its systematically absorbed.

If someone with sides from oral dusteride would be willing to try it topically they would get sides if it was absorbed systematically.

In theory it would work anyway. Unless there was less systematic absorbtion. Either way, if it caused less sides but still was absorbed slightly systematically than it wouldn't matter.

 

[Phillip]

My belief remains that if a topical preperation of dutasteride was a possible effective male pattern baldness treatment, then GKS would have developed this option.
They didnt for whatever reason - ineffective? Dangerous? Impractical?
Or ridiculously expensive. If you need to apply 1ml of 0.5mg Dutateride twice a day everyday then you will find your regeime bursting the £1000 a month line.

How do you explain that minoxidil and finasteride work on frontal hairline/temples in many people yet it wasnt "developed" or approved for this purpose?