Study: Plucking Hairs Will Regenerate New Follicles
- Thread starter bassa
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One brave guinee pig should try it
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If your read carefully, you will notice that a minimum of 200 hairs have to be plucked in order to induce regrowth in neighbor follicles. These 200 hairs have to be very close: in an area with a 5 mm diameter (or a fifth of an inch). Otherwise, no extra regrowth.
Yes, we are talking about mice, because no human (let alone a thinning male) has 200 hairs in an area of 5mm as diamater.
Yes, we are talking about mice, because no human (let alone a thinning male) has 200 hairs in an area of 5mm as diamater.
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Good point Roberto.
In the cited study:
" plucking fewer than 50 refractory telogen hairs did not induce
hair regeneration, while plucking more than 200 hairs did"
And more different when we use a mouse hair model
According this full paper, Dermal papilla cell number specifies hair size, shape and
cycling and its reduction causes follicular decline.
https://www.ncbi.nlm.nih.gov/pubmed/23487317
The pelage of the mouse is composed of four hair types; guard, awl,
auchene and zigzag. ….
The follicles that make guard hairs
form first in embryogenesis and normally continue to make guard
hairs throughout the life of the animal. However, the follicles that
make awls, auchenes and zigzags can make different hair types in
successive hair cycles
BTW it is interesting to review studies regarding number of new hair regrowths in animals
In the cited study:
" plucking fewer than 50 refractory telogen hairs did not induce
hair regeneration, while plucking more than 200 hairs did"
And more different when we use a mouse hair model
According this full paper, Dermal papilla cell number specifies hair size, shape and
cycling and its reduction causes follicular decline.
https://www.ncbi.nlm.nih.gov/pubmed/23487317
The pelage of the mouse is composed of four hair types; guard, awl,
auchene and zigzag. ….
The follicles that make guard hairs
form first in embryogenesis and normally continue to make guard
hairs throughout the life of the animal. However, the follicles that
make awls, auchenes and zigzags can make different hair types in
successive hair cycles
BTW it is interesting to review studies regarding number of new hair regrowths in animals
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+1
tress_dreams
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This study was not in any way at all an attempt at treating alopecia. Follicles were chosen because measuring the outcome was stupid easy. They just need to count the hair. It was all just a novel way of demonstrating organ-level quorum sensing happens, works, and is localized (diameter impacted outcome greatly). Quorum sensing, in something beyond the usual simple bacteria. Perhaps useful in other organs and worth studying in those applications further.
They only briefly theorize on the underlying mechanism of action:
...they locally induce regeneration through the release of substances such as Tnf-a
paraphrasing they mean: "plucking hairs indirectly caused some barely understood sh*t to happen. We don't f*****g care because we demonstrated organ-level quorum sensing..which is cool and helpful."
If only they did care though. Determining the mechanism of action that caused the 5x regrowth could lead to some interesting approaches to inducing a similar reaction; where plucking is not possible. ¯\_(ツ)_/¯
They only briefly theorize on the underlying mechanism of action:
...they locally induce regeneration through the release of substances such as Tnf-a
paraphrasing they mean: "plucking hairs indirectly caused some barely understood sh*t to happen. We don't f*****g care because we demonstrated organ-level quorum sensing..which is cool and helpful."
If only they did care though. Determining the mechanism of action that caused the 5x regrowth could lead to some interesting approaches to inducing a similar reaction; where plucking is not possible. ¯\_(ツ)_/¯
tress_dreams
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Curious if anyone has experimented with increasing FUE yield in a healthy and dense donor area through this approach. Maybe combine similarly small diameter, large follicle count plucking with stem cell treatments in the donor area. Wait for - hopefully denser - regrowth before proceeding with the normal FUE.
It would have to be an appropriately healthy donor area in order to reach quorum - if it works at all. *I need to get a life*
It would have to be an appropriately healthy donor area in order to reach quorum - if it works at all. *I need to get a life*