Study implicating DHA with prostate cancer in finasteride users

[HughJass]

The full text requires a subscription but it's discussed on these blogs:

http://www.marksdailyapple.com/fish-oil ... Telogen Effluvium-cancer/
http://rawfoodsos.com/2011/04/29/will-o ... Telogen Effluvium-cancer/
http://www.futurepundit.com/archives/00 ... 0429150009
http://perfecthealthdiet.com/?p=3338


"The finasteride arm had 78% more high-grade cancers than the placebo arm."

 

[wessneijder]

The full text requires a subscription but it's discussed on these blogs:

http://www.marksdailyapple.com/fish-oil ... Telogen Effluvium-cancer/
http://rawfoodsos.com/2011/04/29/will-o ... Telogen Effluvium-cancer/
http://www.futurepundit.com/archives/00 ... 0429150009
http://perfecthealthdiet.com/?p=3338


"The finasteride arm had 78% more high-grade cancers than the placebo arm."

Yes I have read about this before as well, it seems that the use of 5AR inhibitors increases the risk of high grade prostate cancer, and death. Yet they decrease the risk of low grade, some people have speculated that the incidence of low grade prostate cancer leads to early detection and treatment, which often prevents the progression to high grade malignancy. Finasteride also alters PSA levels, this makes detection harder.

Yet another reason to use androgen receptor blockers, like CB-03-01 instead, which is twice as effective as finasteride anyway.

Where can you get this CB stuff?

 

[Wuffer]

The jury is still out on 5AR inhibitors and prostate cancer; there are currently a few trials going on that indicate it may prevent cancers and reduce overall mortality, but it's still up in the air. DHT is a contributor to prostate cancer, and it makes sense that reducing that could quite possibly reduce prostate cancer incidence. However, as Finfighter said, it alters PSA levels making detection a bit more difficult.

The big finasteride prostate prevention trial showed a 30% reduction in prostate cancer with men taking finasteride.. shortly after, they determined that it also increases risk of more aggressive cancer, then even more research came out that showed this may not be the case.

It's still being considered as a potential treatment. As a person who has watched two family members struggle and succumb to prostate cancer, it would be fantastic news if finasteride/dutasteride could be used as a preventative measure.

When it comes down to it though, a young 20-something guy taking 1mg finasteride for hair loss already has an almost 0% risk of prostate cancer..