Certainly the skin cannot metabolize all of the spironolactone.
One of my personel concerns is in regards to simply over medicating. When does one say enough is enough when trying combat male pattern baldness. For me, I think I have reached my limit with finasteride/minoxidil/nizoral. I feel like I am already spending enough $ on that crap and risking side effects (both long and short term) so I do not want to add in the $ and risks associated with spironolactone.
As far as it's (spironolactone's) safety, it appears to be safe and realtively effective but I am a skeptic. This Dr. lee guy is becoming a millionaire and money pollutes so I am going to take his comments with a grain of salt.
This is all opinion but......our hair follicles and the cells along the area in which male pattern baldness effects are sustained through our blood flow (pretty much like everything in our body). spironolactone is an anti andro product and unless that andro is reduced in the blood flow to the follicles then how can spironolactone be helpful? Cells in the human body do not have a mind of their own so those cells are not just sitting there saying no to the blood flow which sustains them and contains andro. I just don't buy the fact that a cream that is metbolized in the skin can force a cell (or hair follicle) to reject andro. My other issue is in regards to the fact that if this treatment is effective and has no risk then why are we not seeing more people using it to fight male pattern baldness. Many men are desperate for anything that can help as we see finasteride and minoxidil sales skyrocket, why does it appear that spironolactone treatment is less common and less recommended then the big 3 (especially on websites like this in which many of the contributors appear to be very well informed)?
