Safflower rhFGF9 protein may 2-3x hf neogenesis

[FollicleGuardian]

«Safflower contains an rhFGF9 fusion protein that increases Fgf9. Apparently overexpression of Fgf9 results in a two- to threefold increase in the number of neogenic hair follicles.»

Safflower Oil expresses FGF9: https://pubmed.ncbi.nlm.nih.gov/30157831/

FGF9 induces follicle neogenesis after wounding:

Fgf9 from dermal γδ T cells induces hair follicle neogenesis after wounding - PubMed

Understanding molecular mechanisms for regeneration of hair follicles provides new opportunities for developing treatments for hair loss and other skin disorders. Here we show that fibroblast growth factor 9 (Fgf9), initially secreted by γδ T cells, modulates hair follicle regeneration after...

pubmed.ncbi.nlm.nih.gov

 

[Gegen]

Mmmhhh interesting, do you think mixing The ordinary solution 3% resveratrol+3% ferulic acid and some Safflower oil could help upregulating b-catenin nucleation ? If I remember well, Resveratrol mildly phosphorylates gsk3, FA inhibits strongly FGFR1 and slightly FGFR2.

 

[FollicleGuardian]

Mmmhhh interesting, do you think mixing The ordinary solution 3% resveratrol+3% ferulic acid and some Safflower oil could help upregulating b-catenin nucleation ? If I remember well, Resveratrol mildly phosphorylates gsk3, FA inhibits strongly FGFR1 and slightly FGFR2.

A good combo that targets multiple pathways. It may work really good. However I think you would need something more powerful that increases Wnt-signalling, maybe SM or Methyl Vanillate?

 

[Gegen]

A good combo that targets multiple pathways. It may work really good. However I think you would need something more powerful that increases Wnt-signalling, maybe SM or Methyl Vanillate?

Of course, but the point is that it's turbo-cheap. Like <10 euros a month. Also, I'm on the ordinary solution since 3 days and I feel like the penetration is not optimal, it is very oily as the vehicle is a mixture of fatty acids.
So I wonder if inject it in the derme could be more efficient ? I can apply it topically in the 3/4 days after wounding, and then do injection for 3/4 days until the next microneedling session.
Whatever, I'll try it topically only (I dermaroll slightly at 0.5mm when I apply it) for 3 or 4 months and then I will see.