question

[outgrowth]

"Azelaic acid 5%
Proven to inhibit up to 100% of DHT where applied"
in
https://www.xandrox.com/azelaic.htm

If it's so much powerful like this, shouldnt it make living hair follicles thicker with time (using minoxidil too)? Anyone who approves it? Anyone who doesnt?

 

[mvpsoft]

Here's the exact quote from Lee's site:

In vitro, azelaic acid acted as a scavenger of oxy radicals and inhibits a variety of oxidoreductive enzymes including 5-alpha reductase, the enzyme responsible for converting testosterone to DHT. Azelaic acid (0.1 to 3.0 mmol/l) has been shown to produce a competitive concentration dependent inhibition of 5-alpha reductase activity in homogenates of human foreskin.

It is notable that nothing is said about inhibiting 5-alpha reductase on the scalp. That doesn't mean that it doesn't inhibit 5-alpha reductase on the scalp, only that we don't know.