it is spread evenly!
Hi everybody, I am new here in this forum, but not new in the regrowth field...have been using hairloss products for years.
I am a pharmacist, and I would like to tell you all, that finasteride IS spread evenly in the proscar or propecia pills. Unless otherwise is indicated on the pack (such as divitabs, or controll release, retarded etc.) all tabs and pills are made to have same amount of active ingredients in every part of them. It's all part of the manufacturing of tabs and pills. As someone who has made tabs during his studies, I can tell you that a mixture of powders is made, consisting of the active ingredient/s and assisting ingredients such as fillers, glues, waxing agents etc. to give the tab/pill its final size, properties, rigidity, stability under packing, transporting and more.
The mixture of powder is WELL shaked and mixed, for it is tranferred through tubes and pipes in the machine...Moreover, the mixture is poured into the tablet-shaped-wholes as a homogenic powder, and the machine is measuring the amount needed for the wholes by WEIGHT which REQUIERES for a well mixed, homogenic mixture. In fact, making tabs that consist of ingredients that are NOT evenly spread would cost much more, because it means interfering with the process and changing on purpose the manufacturing.
There are tabs and pills on the market that are not evenly spread but those pills are INTENDED to be so, because they are formulated to give a control release AND to be able to be split...Tablets that are made to give a slow release in the body are usually made of a matrix which is made of layers of ingredients. These layers melt and release in the body over time in a certain profile. Splitting such tabs would ruin the matrix and impair the slow release profile. If sush tabs are DESIGNED IN ADVANCE to be split by the manufacturer, one of the technologies to do so is to make a tab that has a splitting line (so that the patient will know where to split it) but is actually made of two parts inside. Each part is made of a matrix that gives a slow release profile, and these two parts are conected to each other to form a whole nice tab. The patient can split the tab (if he consumes 1.5 tabs together, for example) according to the splitting line on the tab and then to get these two parts seperatley. This is a reason why not to spread the ingredients evenly. And of course, if there's no reason to invest that much of money on this kind of formulation the manufacturers WON'T do it.
So, I am SURE that Propecia and Porscar are homogenic pills. However,
a different issue which is still possible is the coating...the coating of the proscar is cut and breakes after cutting the pill. I don't believe that the coating effects the activity of this specific drug...surely it effects the absorption profile, but doesn't change the pharmacologic activity of the drug.
Eliaz.
