Patent for walnut leaves, pericarps...alpha five inhibitor

[michael barry]

http://www.freepatentsonline.com/EP0279010.html

European Patent EP0279010 Kind Code:A2 Link to this page:http://www.freepatentsonline.com/EP0279010A2.html Abstract:A 5 alpha -reductase inhibitor comprising as an effective component an extract from leaves and/or pericarps of a walnut. The inhibitor exhibits high potent 5 alpha -reductase inhibiting activity and high safety, and is thus effective in curing and preventing diseases caused by testosterone, e.g. male-pattern alopecia, hirsutism, prostate cancer and the like...........

These names are on this patent: Inventors:Kitahara, Takashi
Yoshida, Eisaku
Akatsu, Mitsuhiro
Jokura, Yoji
Hattori, Michihiro
Takaishi, Naotake


This patent dates from 1988 though. ...................................I dont know if it was ever tested or pursued.






Spectral DNC has a new product claiming a component in OLIVE OIL is a potent alpha five reductase inhibitor. That sure as hell is new. Here is the verbiage:

"

Phytosterol 5-alpha-reductase inhibitors. Spectral.DNC-L deploys three potent compounds that inhibit the activity of 5-alpha-reductase because that enzyme converts testosterone to dihydrotestosterone (DHT), which damages hair follicles. These phytosterol extracts are olive (standardized with verbascoside), saw palmetto (serenoa repens), and flax seed (standardized with secoisolariciresinol diglucoside). Nanosomes deliver the 5-alpha-reductase inhibitors deep within the scalp.

In patients sensitive to DHT, closely associated with male pattern baldness, the hormone seems to choke follicles by interfering with the enzyme adenylate cyclase. This disruption increases sebum production and decreases hair growth. When hormonal concentrations become high, thick terminal hairs whither to become thin vellus hairs (peach fuzz).

Spectral.DNC-L strongly inhibits the action of 5-alpha-reductase, thus limiting DHT, sebum, and hair loss.

The best inhibitor, olive extract standardized with its active ingredient, verbascoside, blocks 5-alpha-reductase for healthy sebum regulation. Ripe olives contain biophenols, a class of molecule known for antioxidant, anti-inflammatory, and antiviral properties. A major component of the biophenols, verbascoside inhibits 5-alpha-reductase type-2 at a rate 3.5 times greater than the second compound, serenoa repens.

Ive looked and really couldn't find anything on walnuts or olive oil lessening circulating serum levels of DHT or topical application thereof in skin. Flax supposedly sees a MILD reduction in DHT, but one has to take alot of it. Flax stops me up, so its out of the question for me personally.