Nigella Sativa Reduces Pdg2 But.......

[proscar2]

... i think it also inhibits pge2 slighty?
https://www.google.co.uk/url?sa=t&r...e-hair-loss/&usg=AOvVaw3IQFv5QbmzDRLEOVB_S5uu

https://www.google.co.uk/url?sa=t&r...e-hair-loss/&usg=AOvVaw3IQFv5QbmzDRLEOVB_S5uu
https://www.google.co.uk/url?sa=t&r...e-hair-loss/&usg=AOvVaw3IQFv5QbmzDRLEOVB_S5uu
Nigella Sativa shows promise for hair growth promotion in studies
www.drugro.com/nigella-sativa-may-reduce-hair-loss/
Nigella sativa also inhibits NK- KB and its PDG2 regulates hair cycle. Nigella Sativa also contains a constituent called tymoquinon (TQ) which works as both an anti-oxidant and an anti-inflammatory agent. This special compound inhibits bio-chemical factors which promote inflammation that lead to common hair loss ...

 

[whatevr]

I'm going to take it orally.

 

[Trichosan]

One must consider if it is possible to have effects that are specific to scalp inflammation that are not effectively influenced by other compounds. In other words, why would Nigella be effective in inflammation that is causing hairloss, and other anti-inflammatory meds like ibuprofen or even natural anti-inflammation compounds like curcumin would not be? And if androgenic alopecia is at play, there might not be any inflammation at all yet hairloss occurs.

 

[whatevr]

male pattern baldness involves BOTH inflammation and the immune system. Just google 'prostaglandins + inflammation'. You will also find numerous links to various immune components. You don't lose your hair out of thin air. The mechanism IS inflammation, whether you feel it or not. There are not 10 types of male pattern baldness. Just inhibiting PGD2 sufficiently can arrest hair loss, I think westonci proved that, and so will the Setipiprant studies.

 

[Alex Contee]

I add black cumin seed oil (nigella) and a few other things to garnier stemoxydine (I bought it before I wised up about hair loss and figure I might as well put it to use as a vehicle). I have been experimenting with adding a new substance every 3-6 months. I have noticed less inflammation and bulb itch since using black cumin seed oil. Probably need more time to make sure it is not a placebo effect but I am feeling pretty good about it. Unfortunately, I have not noticed any growth from it.

I don't love the fact that it seems to inhibit PGE2 but I think more research is needed. Some details in the study
Cancer chemopreventive potential of volatile oil from black cumin seeds, Nigella sativa L., in a rat multi-organ carcinogenesis bioassay (Apparently I am too new to link to it which seems like a good call)

Edit: I started using it in December.

 

[whatevr]

I add black cumin seed oil (nigella) and a few other things to garnier stemoxydine (I bought it before I wised up about hair loss and figure I might as well put it to use as a vehicle). I have been experimenting with adding a new substance every 3-6 months. I have noticed less inflammation and bulb itch since using black cumin seed oil. Probably need more time to make sure it is not a placebo effect but I am feeling pretty good about it. Unfortunately, I have not noticed any growth from it.

I don't love the fact that it seems to inhibit PGE2 but I think more research is needed. Some details in the study
Cancer chemopreventive potential of volatile oil from black cumin seeds, Nigella sativa L., in a rat multi-organ carcinogenesis bioassay (Apparently I am too new to link to it which seems like a good call)

Edit: I started using it in December.

I don't know if stemoxydine contains alcohol but thymoquinone the active chemical that inhibits PGD2 is soluble in ethanol so you need that in your vehicle to make use of it properly.

A study I found mentioned:
topic formulation containing 0.5% NS essential oil, 3% glycerin, 0.4% lavender essential oil and 60% alcohol to 100 ml.

 

[Trichosan]

I add black cumin seed oil (nigella) and a few other things to garnier stemoxydine (I bought it before I wised up about hair loss and figure I might as well put it to use as a vehicle). I have been experimenting with adding a new substance every 3-6 months. I have noticed less inflammation and bulb itch since using black cumin seed oil. Probably need more time to make sure it is not a placebo effect but I am feeling pretty good about it. Unfortunately, I have not noticed any growth from it.

I don't love the fact that it seems to inhibit PGE2 but I think more research is needed. Some details in the study
Cancer chemopreventive potential of volatile oil from black cumin seeds, Nigella sativa L., in a rat multi-organ carcinogenesis bioassay (Apparently I am too new to link to it which seems like a good call)

Edit: I started using it in December.

I have some black cumin seed oil and find it very peppery to taste. Do you find it has stimulating feel on the scalp?

 

[whatevr]

I made this lotion today. Applied twice, not much change in scalp feel or shedding (still a lot).

 

[Alex Contee]

I don't know if stemoxydine contains alcohol but thymoquinone the active chemical that inhibits PGD2 is soluble in ethanol so you need that in your vehicle to make use of it properly.

A study I found mentioned:
topic formulation containing 0.5% NS essential oil, 3% glycerin, 0.4% lavender essential oil and 60% alcohol to 100 ml.

It contains alcohol. At least enough to dissolve RU up to 6-7%.

I have some black cumin seed oil and find it very peppery to taste. Do you find it has stimulating feel on the scalp?

I have yet to try it without my stemoxydine vehicle which is fairly stimulating on its own. I know black cumin seed oil increases blood flow but if it's stimulating my scalp it is doing so at a much lower level than say peppermint oil.

 

[Workingonit]

I’ve finally had a minor breakthrough.

I’ve been thinning for 9 years. About 2 years ago it became more visible than ever. Basically gone. I’ve tried minoxidil and finasteride but didn’t like the chemicals involved or it affecting my normal bodily functions.

I was thinking I could sit here and tell my whole story spanning almost a decade but let’s cut to the chase.

I’ve been using 50% Glycolic Acid, BSO & DMSO almost every day for about a month now. Scalp peel at least once a week. Paired with scalp massages. I also bought potent BSO and vegetarian capsules and made my own pills. I’ve been on those for 7 days now and I believe it’s helping reduce inflammation.

I have seen the most progress ever.

I have a NW3.

I have the most vellus hairs in my balding areas I’ve ever seen. Only problem is, they’re not terminal. They keep getting longer and longer every few days. Under an angle of light, if those hairs were terminal all my hair would be back. Seeing this just further proves to me that hair follicles can always be revived. They’re dormant I guess. I will continue my journey and update if the hairs turn terminal as well as post many pictures with progress. But only if they turn terminal.

I’ve been an observer for most of my journey, this is my first post about my breakthrough. I plan on growing all my hair back. Well I plan on making those hairs thicker, terminal. It has already grown back in my eyes. It has been my obsession since I started losing my beautiful hair. Feels good to finally see progress. I believe right now, it’s a matter of time before those hairs get more oxygen thus making them terminal. At this rate. I’ll have my hair back within 6 months. They just need to turn terminal.

All advice/help is welcome. If you know of a natural way to thicken hair. Let me know. I’ve also reduced my meat consumption as I’ve read a diet low in meat reduced PGD2.

 

[Tommybommy1363]

male pattern baldness involves BOTH inflammation and the immune system. Just google 'prostaglandins + inflammation'. You will also find numerous links to various immune components. You don't lose your hair out of thin air. The mechanism IS inflammation, whether you feel it or not. There are not 10 types of male pattern baldness. Just inhibiting PGD2 sufficiently can arrest hair loss, I think westonci proved that, and so will the Setipiprant studies.

How do you know there aren’t different types of male pattern baldness? I for one think it is likely a group of heterogeneous disorders

 

[NotInmywatch]

I’ve finally had a minor breakthrough.

I’ve been thinning for 9 years. About 2 years ago it became more visible than ever. Basically gone. I’ve tried minoxidil and finasteride but didn’t like the chemicals involved or it affecting my normal bodily functions.

I was thinking I could sit here and tell my whole story spanning almost a decade but let’s cut to the chase.

I’ve been using 50% Glycolic Acid, BSO & DMSO almost every day for about a month now. Scalp peel at least once a week. Paired with scalp massages. I also bought potent BSO and vegetarian capsules and made my own pills. I’ve been on those for 7 days now and I believe it’s helping reduce inflammation.

I have seen the most progress ever.

I have a NW3.

I have the most vellus hairs in my balding areas I’ve ever seen. Only problem is, they’re not terminal. They keep getting longer and longer every few days. Under an angle of light, if those hairs were terminal all my hair would be back. Seeing this just further proves to me that hair follicles can always be revived. They’re dormant I guess. I will continue my journey and update if the hairs turn terminal as well as post many pictures with progress. But only if they turn terminal.

I’ve been an observer for most of my journey, this is my first post about my breakthrough. I plan on growing all my hair back. Well I plan on making those hairs thicker, terminal. It has already grown back in my eyes. It has been my obsession since I started losing my beautiful hair. Feels good to finally see progress. I believe right now, it’s a matter of time before those hairs get more oxygen thus making them terminal. At this rate. I’ll have my hair back within 6 months. They just need to turn terminal.

All advice/help is welcome. If you know of a natural way to thicken hair. Let me know. I’ve also reduced my meat consumption as I’ve read a diet low in meat reduced PGD2.

I've had good results with 1% cetirizine in 96° ethanol sprayed every night. Started to see regrowth at the hairline only after 7 months, though.
I guess PRP is too expensive where you live? I'm planning to add LLLT as well. good luck

 

[Workingonit]

I've had good results with 1% cetirizine in 96° ethanol sprayed every night. Started to see regrowth at the hairline only after 7 months, though.
I guess PRP is too expensive where you live? I'm planning to add LLLT as well. good luck

I’ll look into it. I’m estatic about my regrowth. Hoping they turn terminal soon. I tried PRP a few years ago and spent about a grand for a few sessions. Didn’t see any improvement. I believe the scalp peels help a lot bc clogged pores. Between the BSO, GA & DMSO. One if not all of them must be DHT killers. I even did 90 days nofap and never got results like I have now.

 

[Fgsfds]

I’ll look into it. I’m estatic about my regrowth. Hoping they turn terminal soon. I tried PRP a few years ago and spent about a grand for a few sessions. Didn’t see any improvement. I believe the scalp peels help a lot bc clogged pores. Between the BSO, GA & DMSO. One if not all of them must be DHT killers. I even did 90 days nofap and never got results like I have now.

That's a super interesting and unique stack you got there. What made you try those? Also, you should make your own thread if your results are good enough for pics.

 

[jamesbooker1975]

... i think it also inhibits pge2 slighty?

https://www.google.co.uk/url?sa=t&rct=j&q=&esrc=s&source=web&cd=8&cad=rja&uact=8&ved=0ahUKEwjF25Wm4q_ZAhVQy6QKHd4oCFQQFghpMAc&url=http://www.drugro.com/nigella-sativa-may-reduce-hair-loss/&usg=AOvVaw3IQFv5QbmzDRLEOVB_S5uu
Nigella Sativa shows promise for hair growth promotion in studies
www.drugro.com/nigella-sativa-may-reduce-hair-loss/
Nigella sativa also inhibits NK- KB and its PDG2 regulates hair cycle. Nigella Sativa also contains a constituent called tymoquinon (TQ) which works as both an anti-oxidant and an anti-inflammatory agent. This special compound inhibits bio-chemical factors which promote inflammation that lead to common hair loss ...

Jesus, Hidrocortisone plus minoxidil. That is the Answer and that was why Xandrox was so great. Inhibit all the inflamation, then add minoxidil to increase the Pge2 .
At least 2 papers on pubmed show that it works.
And not, it will not , thin, your skin.

 

[Workingonit]

That's a super interesting and unique stack you got there. What made you try those? Also, you should make your own thread if your results are good enough for pics.

I originally started with MSM supplements (sulfur) as it extends the hair cycle. Through further research, I stumbled upon DMSO which is liquid sulfur. Found out it takes whatever's on the surface into your bloodstream. I started buying essential oils and mixing them but soon realized I needed a carrier oil that doesn't clog the pores like almond oil or jojoba oil. Slightly used DMSO w/ essential oils but got nothing. The almond oil kept my scalp hydrated so that was cool to find out so it didn't dry out. But no results after a few months so I moved on. Got into dermarolling heavy w/ minoxidil. Didn't see much progress after 6 months but did notice my scalp was thick by the puncture holes. I wanted to do it naturally so I quit minoxidil. I kept doing research everyday. Saw the progress of scalp peels. I questioned my shiny thick scalp. Bought some salicylic acid and glycolic acid from a lab website. Experimented. Sometimes mixed the 2. Tried to do at least 1 scalp peel every couple weeks. I tested both acids individually and I responded better w/ GA. GA also forms new collagen from within the cell. Used it for a month, noticed my scalp would grow back thicker and stronger from the glycolic acid and started seeing little blonde hairs sprout. Also noticed my scalp wasn't always shiny like it once was. After the peels I could clearly see the pores on my head with no shine. Just a matte look. Did more research and started looking into what actually had to happen for hair to grow & how to speed it up. So it had to reach the lowest level under the scalp to start the bulb or something like that but if that's attacked by DHT and a bunch of clogged pores w/ layers of skin. How? So, scalp peel and soon after, GA on the affected area. Then DMSO on top of it. The DMSO will carry the glycolic acid to the deep layers of the scalp and kill the DHT. It stings a little but I had to try something different to get different results plus the sting only lasted 5-10 seconds. After doing that a few times I noticed those blonde hairs came out further. That was all I needed to see.

Recently, stumbled upon BSO by looking for the closest oil w/ minerals etc to irish sea moss. Plus read how ppl were using it for thinning hair. Bought some potent Ethiopia BSO. Started taking a tablespoon of BSO daily because I saw a youtube video of how it brings more oxygen to blood cells. And from my research it was really good stuff. Started applying it to my scalp and it also hydrated my scalp. Combined it all, came up w/ glycolic acid and DMSO to kill the DHT and BSO to hydrate the scalp and anti-inflammation. Been repeating that over and over for about a month now as well as taking BSO vegetarian capsules I made bc I got tired of taking the BSO by tablespoon due to tart taste. The hairs keep getting longer and more visible at an angle under the light. I can touch my bald area and feel the mini hairs for the first time in years. I tried to include as much detail as possible without going off into the abyss. Another mistake I made was using EMU oil. I believe that sped up the healing too fast for it to "reset". Once I dropped EMU oil from the equation. I saw results.