male pattern baldness theory discrepancies

[ukmale24]

Correct me if i'm wrong as i'm no way a science boff, but aren't the long standing theories of (1) the production of DHT causing male pattern baldness and (2) stem cells becoming deactivated, both a clash as only one can be right. Take a hair transplant for example, hair is being transplanted into the same cell so can the stem cell theory have any validity? Or am i confusing stem cells with skin cells? Like i said i'm no science boff so i don't know the difference if there is one.

 

[cristi2011]

I don't think one theory excludes another. Think about it: maybe DHT attacks all the hair, but hair from back and sides can ovverride DHT attack due to the fact that stem cells from there are active and regenerate the hair.
I think if one can re-activate dormant stem cells from the male pattern baldness areas, DHT would no longer be a problem since the follicle could simply regenerate due to stem cells.
So i think the main cause for male pattern baldness are mainly the inactive stem cells from male pattern baldness area, and because of this DHT can attack the hair.

 

[ukmale24]

But then how, when somebody has a hair transplant on the crown, temples, or hairline, does the hair stay? Because they're being transplanted into the same cells as were there before.

 

[Bryan]

But then how, when somebody has a hair transplant on the crown, temples, or hairline, does the hair stay? Because they're being transplanted into the same cells as were there before.

No, they are different hair follicle cells which are transplanted from the permanent regions, hence they don't have androgen receptors.

Huh?? You think that transplanted hair follicles don't have androgen receptors? Where'd you get THAT idea?? :dunno: :laugh:

 

[Bryan]

This is what I meant to write. '' No, they are different hair follicle cells which are transplanted from the permanent regions, hence they don't have androgen receptors that are genetically preprogrammed to initiate minaturization and apoptosis., once androgens attach.

Androgen receptors aren't programmed to initiate miniaturization. Individual hair follicles are programmed to do that!

 

[Bryan]

To avoid confusing newbies as much as possible, I think we should speak with a reasonable degree of precision. It's not reasonable to say that androgen receptors are "programmed" in any way, shape, or fashion.